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TranscriptomicsGene expression profiling of novel antigen presenting cells (APC) inducing pathogenic T helper cells of lupus
In lupus autoimmunity, pathogenic IgG autoantibodies that fix complement and bind FcGammaR on inflammatory cells, are produced with help from T helper (Th1 and Th17) cells specific for peptides from nucleosomes of apoptotic cells; and these Th cells also infiltrate vital organs (1-9). Macrophages (...
ORGANISM(S): Mus musculus 
2012-06-20 | E-GEOD-36284 | biostudies-arrayexpress
UnknownReciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.
Not available
S-EPMC4199239 | biostudies-literature
TranscriptomicsA Methodology for Utilization of Predictive Genomic Signatures in FFPE Samples
Purpose: Gene expression signatures developed to measure the activity of oncogenic signaling pathways have been used to dissect the heterogeneity of tumor samples and to predict sensitivity to various cancer drugs that target components of the relevant pathways, thus potentially identifying therapeu...
ORGANISM(S): Homo sapiens 
2011-06-24 | E-GEOD-29598 | biostudies-arrayexpress
TranscriptomicsStrand-specific transcriptomes of Saccharomyces cerevisiae and Saccharomyces paradoxus
Background: Recent studies have demonstrated that antisense transcription is pervasive in budding yeasts and is conserved between Saccharomyces cerevisiae and S. paradoxus. While studies have examined antisense transcripts of S. cerevisiae for inverse transcription in stationary phase and stress con...
ORGANISM(S): Saccharomyces cerevisiae 
2014-06-09 | E-GEOD-58319 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human bronchial epithelial cells overexpressing the lung developmental transcription factors TTF1, NKX2-8 and PAX9
We investigated the clinical implications of lung developmental transcription factors (TTF-1, NKX2-8, and PAX9) which we recently discovered as cooperating oncogenes activated by way of gene amplification at chromosome 14q13 in lung cancer. Using stable transfectants of human bronchial epithelial ce...
ORGANISM(S): Homo sapiens 
2009-04-10 | E-GEOD-9212 | biostudies-arrayexpress
UnknownSalvage Boron Neutron Capture Therapy for Malignant Brain Tumor Patients in Compliance with Emergency and Compassionate Use: Evaluation of 34 Cases in Taiwan.
Not available
S-EPMC8071294 | biostudies-literature
UnknownPsychosocial outcomes among adults with type 1 diabetes using a tubeless automated insulin delivery system compared with sensor augmented pump therapy: A randomised, parallel-group clinical trial sub-study.
Not available
S-EPMC12916430 | biostudies-literature
UnknownQuantifying Duration of Proteinuria Remission and Association with Clinical Outcome in IgA Nephropathy.
Not available
S-EPMC8054888 | biostudies-literature
UnknownStroke genetics informs drug discovery and risk prediction across ancestries.
Not available
S-EPMC9524349 | biostudies-literature
UnknownTrans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
Not available
S-EPMC4719169 | biostudies-literature
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