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GenomicsRNAi promotes heterochromatic silencing through replication-coupled release of RNA pol II (ChIP-seq)
Heterochromatin comprises tightly compacted repetitive regions of eukaryotic chromosomes. The inheritance of heterochromatin through mitosis requires RNA interference (RNAi), which guides histone modification 1 during the DNA replication phase of the cell cycle2. Here, we show that the alternating a...
ORGANISM(S): Schizosaccharomyces pombe 
2011-07-29 | E-GEOD-31016 | biostudies-arrayexpress
UnknownPersonalization of CM Injection Protocols in Coronary Computed Tomographic Angiography (People CT Trial).
Not available
S-EPMC7201621 | biostudies-literature
TranscriptomicsTranscription profiling of E. coli CSH50 wild type and hupA::cm hupB::kan double mutant cells
Comparison of transcript profiles of E. coli CSH50 wild-type and CSH50 hupA::cm hupB::kan double mutant cells to distinguish between the genes expressed either in the presence or absence of HU during log phase.
ORGANISM(S): Escherichia coli 
2008-12-01 | E-MEXP-1742 | biostudies-arrayexpress
TranscriptomicsGlobal transcriptomic changes following N-deprivation in Nannochloropsis oceanica IMET1: Illumina sequencing
Limited systems-level understanding of oil synthesis in wild oleaginous algae has hindered the development of microalgal feedstock. Nannochloropsis is a small unicellular microalgae widely distributed in oceans and fresh water. In many large-scale and pilot-scale outdoor cultivation facilities, Nann...
ORGANISM(S): Nannochloropsis oceanica 
2014-05-14 | E-GEOD-42508 | biostudies-arrayexpress
GenomicsDifferent nucleosomal landscapes at early and late replicating origins in Saccharomyces cerevisiae
Sequencing of mononucleosomal DNA during G1 and S phases in Saccharomyces cerevisiae Samples from mononucleosomal DNA from WT and rpd3 mutant strains (W303-1a background) in G1 or in S phase in the presence of 0.2 M HU were sequenced (Illumina Genome Analyzer IIx) using the single-end read protocol
ORGANISM(S): Saccharomyces cerevisiae 
2014-09-09 | E-GEOD-54377 | biostudies-arrayexpress
TranscriptomicsOverexpression of GmDof4 from Soybean Significantly Enhances the Lipid Content of Chlorella ellipsoidea
Here, we transferred GmDof4 from soybean (Glycine max), a transcription factor affecting content of lipid in Arabidopsis, into C. ellipsoidea and found that the expression of GmDof4 significantly enhanced the lipid content by maximum 57.21%, shifted the content of different fatty acids, but did not ...
ORGANISM(S): Pseudochlorella pringsheimii 
2014-04-16 | E-GEOD-37473 | biostudies-arrayexpress
TranscriptomicsInnate and adaptive immunity in zebrafish: time course (zebrafish)
The interaction between fungal pathogen and host innnate and adaptive immunity during infection is a complex and dynamic process. To resolve this, we chose the zebrafish model organism as the host to study C. albicans infection via systems biology approach. Transcriptome microarray data and histolog...
ORGANISM(S): Danio rerio 
2014-11-03 | E-GEOD-51603 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. pombe reveals Cyclin dependent kinase inhibits re-initiation of a normal S-phase program during G2
To achieve faithful replication of the genome once in each cell cycle, re-initiation of S-phase is prevented in G2 and origins are restricted from re-firing within S-phase. We have investigated the block to re-replication during G2 in fission yeast. The DNA synthesis that occurs when G2/M cyclin d...
ORGANISM(S): Schizosaccharomyces pombe 
2009-05-13 | E-MTAB-105 | biostudies-arrayexpress
ProteomicsRegulatory phosphosite on Mec1 and control of RNAP11 and PIII during replication stress
Yeast sensor checkpoint kinase Mec1 is phosphorylated at Ser1991 upon HU replication stress. The phospho-accepter mutant (mec1-S1991A) confers HU sensitivity and synthetic sickness with the mutants that aggravate replication and transcription collision. To understand how the entire chromatin proteom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-28 | PXD027337 | Pride
Lc-msms Mec1 Yeast Chromatome Phosphoproteomics Replication stress 
UnknownSUMOylation controls Hu antigen R posttranscriptional activity in liver cancer.
Not available
S-EPMC11025316 | biostudies-literature
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