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Human blood plasma was depleted using an Agilent Multiple Affinity Removal Hu-6 column
ORGANISM(S): Homo sapiens (Human) 
2012-07-20 | PRD000631 | Pride
C/EBPb is an auto-repressed protein that becomes posttranslationally activated by Ras-MEK-ERK signalling. C/EBPb is required for oncogene-induced senescence (OIS) of primary fibroblasts, but also displays pro-oncogenic functions in many tumour cells. Here, we show that C/EBPb activation by H-RasV12 ...
ORGANISM(S): Mus musculus 
In this study, we have performed comparative gene expression profiling of primary tonsil epithelial cells with the EBV-positive NPC cell line C666.1 using a human gene array. Differences in cellular gene expression was compared using RNA isolated from C666-1 cells and primary tonsil epithelial cells...
ORGANISM(S): Homo sapiens 
In Mycobacterium tuberculosis, the efflux pump, EfpA, plays an essential but uncharacterised role in its physiology and antibiotic tolerance. In this study, an ATc-inducible CRISPR interference (CRISPRi) system was introduced into M. tuberculosis to knock-down the expression of efpA and determine an...
ORGANISM(S): Mycobacterium tuberculosis 
Polyketide synthases (PKSs) are modular enzymes with exceptional potential as biocatalysts for producing non-native compounds. Here, we report the first PKS-based pathway for adipic acid (AA), an industrial monomer for nylon production, by engineering one of the most extensively hybridized PKS syste...
ORGANISM(S): Pseudomonas putida KT2440 
2026-09-07 | PXD069956 | Pride
ICU acquired weakness (ICUAW) is a complication of critical illness characterized by structural and functional impairment of skeletal muscle that may persist for years after ICU discharge with many survivors developing protracted courses with few regaining functional independence. Elucidating molec...
ORGANISM(S): Homo sapiens 
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