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ProteomicsBCAT1 Confers Resistance to EGFR TKIs through α-KG-dependent Epigenetic Regulation of the Glycolysis Pathway in NSCLC
Epidermal growth factor receptor (EGFR) mutations are leading oncogenic drivers in non-small cell lung cancer (NSCLC). Many third-generation EGFR tyrosine kinase inhibitors (TKIs) have been developed to target EGFR T790M and activating mutations. Osimertinib (AZD9291) was the first approved drug and...
ORGANISM(S): Homo Sapiens 
2023-07-14 | PXD043776 |
ProteomicsDARTS-MS chemoproteomic profiling of ginkgolide J-associated protease-susceptibility candidate proteins in rat PASMC lysates
This dataset contains DIA-MS raw files and processed DIA-NN results from a DARTS-MS chemoproteomic experiment designed to identify ginkgolide J-associated protease-susceptibility candidate proteins in primary rat pulmonary artery smooth muscle cell (PASMC) lysates. The experiment included three grou...
ORGANISM(S): Rattus Norvegicus 
2026-05-25 | PXD078800 |
ProteomicsRACK7 Senses and Fine-Tunes Enhancer Activity
RACK7 senses enhancer activity changes and facilitates their activation
ORGANISM(S): Homo Sapiens 
2025-05-26 | PXD058592 |
ProteomicsAntifungal potential of naphthoquinone derivatives: Screening of shikonin-based compounds and mechanistic insights into 5,8-dihydroxy-1,4-naphthoquinone against Candida albicans in vitro and in vivo
These data present the mass spectrometry results from the proteomic profiling of PNP-02 against Candida albicans
ORGANISM(S): Candida Albicans 
2026-01-28 | PXD073742 |
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