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MetabolomicsSubcellular antibiotic visualization reveals a dynamic drug reservoir in infected macrophages
Tuberculosis, caused by the intracellular pathogen Mycobacterium tuberculosis, remains the world's deadliest infectious disease. Sterilizing chemotherapy requires at least 6 months of multidrug therapy. Difficulty visualizing the subcellular localization of antibiotics in infected host cells means t...
2020-12-07 | MTBLS959 | MetaboLights
UnknownThe impact of B-cell-directed therapy on SARS-CoV-2 vaccine efficacy in chronic lymphocytic leukaemia.
Not available
S-EPMC9111753 | biostudies-literature
UnknownHydraulic performance of a pre-aerated stilling basin: Experimental study.
Not available
S-EPMC11761096 | biostudies-literature
UnknownAdaptive Printing of Conductive Microfibers for Seamless Functional Enhancement Across Diverse Surfaces and Shapes
Not available
S-EPMC12287195 | biostudies-literature
UnknownReal-Time Spectral Library Matching for Sample Multiplexed Quantitative Proteomics.
Not available
S-EPMC11554524 | biostudies-literature
ProteomicsProteomics data of extracellular vesicles, which are specifically derived from testicular macrophage cells within the mouse testis, offer detailed and comprehensive insights into the unique biochemical compositions and potential roles of these vesicles in the testicular microenvironment.
Testosterone synthesis in male mammals occurs predominantly in testicular Leydig cells (LCs), a process that is energetically demanding and results in cellular component damage. Despite this, LCs are long-lived and rarely renew, suggesting the presence of specialized mechanisms to maintain LCs homeo...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-24 | PXD059652 | Pride
Testicular macrophage cells -evs 
GenomicsEpigenetic modifications and chromosome conformations of the beta globin locus throughout development
Human embryonic stem cells provide an alternative to using human embryos for studying developmentally regulated gene expression. The co-expression of high levels of embryonic epsilon and fetal gamma globin by the hESC-derived erythroblasts allows the interrogation of epsilon globin regulation at the...
ORGANISM(S): Homo sapiens 
2015-01-26 | E-GEOD-35375 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human fetal liver hematopoietic stem and progenitor cells (HSPC) in culture
One of the long-standing goals in the field has been to establish a culture system that would allow maintenance of HSC properties ex vivo. In the absence of such system, the ability to model human hematopoiesis in vitro has been limited, and there has been little progress in the expansion of human H...
ORGANISM(S): Homo sapiens 
2013-01-31 | E-GEOD-34972 | biostudies-arrayexpress
ProteomicsProteomics data of extracellular vesicles, which are specifically derived from Leydig cells or testicular macrophage cells respectively within the mouse testis, offer detailed and comprehensive insights into the unique biochemical compositions and potential roles of these vesicles in the testicular microenvironment.
Testosterone synthesis in male mammals occurs predominantly in testicular Leydig cells (LCs), a process that is energetically demanding and results in cellular component damage. Despite this, LCs are long-lived and rarely renew, suggesting the presence of specialized mechanisms to maintain LCs homeo...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-24 | PXD059780 | Pride
Leydig cells-evs 
TranscriptomicsTranscriptional environment and chromatin modifications interplay decides globin expression patterns.
Background: Developmental stage-specific globin expression is a complex phenomenon that involves both trans- and cis-acting elements. While functional analyses ensuing recent genome-wide association studies have highlighted the important roles of trans-factors in regulating hemoglobin expression, th...
ORGANISM(S): Homo sapiens 
2012-08-19 | E-GEOD-31523 | biostudies-arrayexpress
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