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ProteomicsCross-link MS analysis of human 26S proteasome in complex with RPN13:UCHL5 (without substrate).
This project investigates how the human 26S proteasome recognizes and processes proteins tagged with K11/K48-branched ubiquitin chains, which signal for rapid degradation during cell cycle progression and proteotoxic stress. Using cryo-electron microscopy (cryo-EM), the study uncovers a novel K11-li...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD064931 | Pride
Rpn13 Proteasome Uchl5 26s 
ProteomicsCross-link MS analysis of human 26S proteasome in complex with RPN13:UCHL5 (with substrate).
This project investigates how the human 26S proteasome recognizes and processes proteins tagged with K11/K48-branched ubiquitin chains, which signal for rapid degradation during cell cycle progression and proteotoxic stress. Using cryo-electron microscopy (cryo-EM), the study uncovers a novel K11-li...
ORGANISM(S): Homo sapiens (Human) 
2025-09-22 | PXD064932 | Pride
K11/k48 ubiquitin Rpn13 Proteasome Uchl5 26s Branched ubiquitin 
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
UnknownImplicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Not available
S-EPMC9793579 | biostudies-literature
UnknownA multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Not available
S-EPMC9388392 | biostudies-literature
UnknownTransforming jet flavour tagging at ATLAS.
Not available
S-EPMC12804921 | biostudies-literature
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Not available
S-EPMC11410654 | biostudies-literature
UnknownNew genetic loci link adipose and insulin biology to body fat distribution.
Not available
S-EPMC4338562 | biostudies-literature
UnknownImpact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries.
Not available
S-EPMC10783642 | biostudies-literature
UnknownGenetic studies of body mass index yield new insights for obesity biology.
Not available
S-EPMC4382211 | biostudies-literature
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