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Our work recognized heterogeneous nuclear ribonucleoprotein R (hnRNPR) is a master regulator of m6A-dependent pre-mRNA splicing. Genetic mutation in HNRNPR leads to asthenoteratozoospermia in both humans and mice, culminating in complete sterility. Mechanistically, genetic ablation of Hnrnpr manifes...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-13 | PXD067981 | Pride
Cholangiocarcinoma whole genome sequencing data
This dataset contains whole genome sequencing FASTQ data for 12 cholangiocarcinoma tumor samples, and their matched normal samples. These 12 samples are in addition to 59 samples available in dataset EGAD00001001988, and consist of patients from Thailand, Romania, and Singapore. Paired-end sequencin...
Cholangiocarcinoma (CCA) is a hepatobiliary malignancy exhibiting high incidence in countries with endemic liver-fluke infection. We analyzed 489 CCAs from 10 countries, combining whole-genome (71 cases), targeted/exome, copy-number, gene expression, and DNA methylation information. Integrative clus...
Proteomics dataset of COVID-19 and control patients
ORGANISM(S): Homo Sapiens 
2021-10-14 | PXD029023 |
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