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This study aimed to investigate the global effect of Chinese medicine formula Pien Tze Huang on hepatocellular carcinoma (HCC) compared with the anti-tumor agent sorafenib based on tandem mass tag label proteomic and phosphoproteomic analysis in addition to parallel reaction monitoring verification.
ORGANISM(S): Mus Sp. Mus Musculus 
We found that AhR, a unique chemical sensor, is critical in controlling mast cell differentiation, growth and function in vitro and in vivo. This study seeks to further the understanding of the mechanisms of how AhR control mast cell homeostasis. Three different batches of bone marrow derived mast c...
ORGANISM(S): Mus musculus 
Mutations in the human gene encoding the neuron-specific Eag1 voltage-gated K+ channel are associated with neurodevelopmental diseases, indicating an important role of Eag1 during brain development. A disease-causing Eag1 mutant channel is linked to defective protein stability that involves enhanced...
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023984 | Pride

Metabolic dysregulation may serve as a pivotal driver of inflammatory bowel disease, with the crosstalk between metabolism and the immune system emerging as a critical research focus. Ulcerative colitis patients exhibit enhanced glycolysis but suppressed ...

2026-06-24 | MTBLS12440 | MetaboLights
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