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GenomicsGenome-wide comparison of DNA hydroxymethylation in mouse embryonic stem cells and neural progenitor cells by relative quantitative hMeDIP-seq
DNA hydroxymethylation (5hmC) represents a new layer of epigenetic regulation in addition to DNA methylation (5mC). The genome-wide patterns of 5hmC distribution in many tissues and cells have recently been revealed by hydroxymethylated DNA immunoprecipitation (hMeDIP) followed by high throughput se...
ORGANISM(S): Mus musculus 
2013-03-08 | E-GEOD-40810 | biostudies-arrayexpress
ProteomicsHuman Hippo cancer mutation proteins TAP-LC-MS
The Hippo pathway is a commonly altered signaling pathway involved in cancer initiation and progression; however, exactly how this pathway becomes dysregulated to promote human cancer development has not been fully understood. In this study, we systematically analyzed the Hippo somatic mutations der...
ORGANISM(S): Homo sapiens (Human) 
2024-10-18 | PXD049472 | Pride
Somatic mutations Cancer The hippo pathway 
ProteomicsA liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs from MLL-AF9+ AML mice
We performed a liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs isolated from MLL-AF9-driven AML mice
ORGANISM(S): Mus Musculus 
2022-10-09 | PXD037217 |
ProteomicsProteins interact with GADD45g in c-kit+ BM cells of wild-type mice
Proteins detected by LC-MS/MS by anti-GADD45g IP in c-kit+ BM cells of wild-type mice.
ORGANISM(S): Mus Musculus 
2023-01-05 | PXD039261 |
Proteomicsthe proteomics of IGFBP6 in endothelial cells (HUVECs)
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2024-05-13 | PXD052204 |
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