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ProteomicsA liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs from MLL-AF9+ AML mice
We performed a liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs isolated from MLL-AF9-driven AML mice
ORGANISM(S): Mus Musculus 
2022-10-09 | PXD037217 |
ProteomicsProteins interact with GADD45g in c-kit+ BM cells of wild-type mice
Proteins detected by LC-MS/MS by anti-GADD45g IP in c-kit+ BM cells of wild-type mice.
ORGANISM(S): Mus Musculus 
2023-01-05 | PXD039261 |
ProteomicsProteomics of malignant transformation of prostate WPMY-1 cells induced by arsenite
Proteomics of immortalized prostate myofibroblast cell line WPMY-1 treated by arsenite was performed and 517 differentially expressed proteins (DEPs) were identified.
ORGANISM(S): Homo Sapiens 
2023-11-10 | PXD046880 |
ProteomicsApoptotic vesicles resist oxidative damage in noise-induced hearing loss through activation of FOXO3a-SOD2 pathway
The purpose of this study is to investigate the therapeutic effect of MSC-derived apoVs treatment on NIHL and the potential mechanism of resisting oxidative stress damage in hair cells, as well as the distribution of apoptotic vesicles in the inner ear. The study provided a new direction for the tre...
ORGANISM(S): Homo Sapiens 
2023-03-20 | PXD040989 |
ProteomicsDiscovery of 180055 as a PROTAC degrader for Treating Cancers
PARP1 is an abundant nuclear protein that is involved in a number of biological processes linked to cellular stress responses. PARP1 inhibitors (PARPi) are known to kill tumor cells via two mechanisms (PARP1 catalytic inhibition and PARP1 trapping). In this work we discovered a PROTAC degrader of PA...
ORGANISM(S): Homo Sapiens 
2023-05-18 | PXD042311 |
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