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Osteoblasts are a key component of the endosteal hematopoietic stem cell (HSC) niche and have long been recognized with strong hematopoietic supporting activity. Osteoblast conditioned media (OCM) enhances the growth of hematopoietic progenitors in culture and modulate their engraftment activity. We...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-15 | MSV000088384 | MassIVE
This study explored the role of peroxiredoxin 6 (Prdx6) non-selenium glutathione peroxidase (NSGPx) activity on the regulation of beef tenderization during post-mortem aging periods of up to 168 h. Shear force, NSGPx activity, differential protein expression, heat shock protein 70 (HSP70), heat shoc...
ORGANISM(S): Bos Taurus 
2025-01-28 | PXD060488 |
With the growing antibiotic resistance of Staphylococcus aureus, it is urgent to discover new antimicrobials to solve this problem. By bacterial growth based high-throughput screening, we identified two compounds, C218-0546 and STK848198, with effective antimicrobial activity against S. aureus. This...
ORGANISM(S): Staphylococcus Aureus 
To gain a deeper insight into the residual SARS-CoV-2 peptides after degradation, we directly detected fragments (lower than 10 (kilodalton) kDa) of degraded SARS-CoV-2 via LC-MS, and overlapped these with the 3D crystal structure of SARS-CoV-2 proteins.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
Proteomic analysis of hydrolase levels in the lysosomes from macrophages stimulated with or without LPS via liquid chromatography–mass spectrometry (LC-MS), highlighting the expected LPS-induced increase in accumulation of proteases, ribonucleases (RNase) and other hydrolases.
ORGANISM(S): Mus Musculus 
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
To investigate the degradation activity of proteases inside lysosomal "TRAP", we conducted proteomic analysis of lysosomal "TRAP" with trapped authentic SARS-CoV-2.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
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