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TranscriptomicsPhenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus
We report the application of RNA sequencing technology for high-throughput profiling of gene expression responses to human rhinovirus infection at 24 hours in air-liquid interface human airway epithelial cell cultures derived from 6 asthmatic and 6 non-asthmatic donors. RNA-seq analysis identified ...
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-61141 | biostudies-arrayexpress
GenomicsIdentification and Characterization of Hoxa9 Binding Sites in Hematopoietic Cells
The clustered homeobox proteins play crucial roles in development, hematopoiesis and leukemia yet the targets they regulate and their mechanisms of action are poorly understood. Here, we identified the binding sites for Hoxa9 and the Hox cofactor Meis1 on a genome-wide level and profiled their asso...
ORGANISM(S): Mus musculus 
2011-12-04 | E-GEOD-33509 | biostudies-arrayexpress
ProteomicsLENG8 mediates nuclear retention and degradation of misprocessed mRNAs and noncoding RNAs
Incompletely processed and misprocessed mRNAs as well as numerous noncoding RNAs are retained in the nucleus and often degraded, and defects in this quality control mechanism have been linked to various diseases, including cancer and neurodegeneration. However, the underlying mechanisms remain poorl...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD065356 | Pride
Misprocessed rnas Rna nuclear retention Rna degradation Leng8 
UnknownDissection of major QTLs and candidate genes for seedling stage salt/drought tolerance in tomato.
Not available
S-EPMC11613539 | biostudies-literature
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
Unknownp97/VCP is highly expressed in the stem-like cells of breast cancer and controls cancer stemness partly through the unfolded protein response.
Not available
S-EPMC7969628 | biostudies-literature
UnknownRNF12 is regulated by AKT phosphorylation and promotes TGF-β driven breast cancer metastasis.
Not available
S-EPMC8748510 | biostudies-literature
UnknownMulti-omics analyses reveal bacteria and catalase associated with keloid disease.
Not available
S-EPMC10749884 | biostudies-literature
ProteomicsMetabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
Metabolomic profiling reveals 5-Hydroxylysine and 1-Methylnicotinamide are metabolic indicators of keloid severity
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032290 |
GenomicsBase-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in Acute Myeloid Leukemia
Here we used Illumina NGS for high-throughput profiling of the DNA methylome in two human colon cancer derived cell lines, two human normal bone marrow CD34+ controls and in five human Acutre Myeloid Leukeima patient samples. These data can be used to determine the CpG cytosine methylation pattern ...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-37454 | biostudies-arrayexpress
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