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TranscriptomicsCell-to-cell gene expression variability followed by reinforcement progressively segregates lineages in the early mouse embryo
Mammalian embryonic development begins with the specification and segregation of the two extra-embryonic lineages, trophectoderm and primitive endoderm, from the pluripotent embryonic lineage, the epiblast. To establish a map of epiblast (EPI) versus primitive endoderm (PrE) lineage segregation whic...
ORGANISM(S): Mus musculus 
2013-11-26 | E-MTAB-1681 | biostudies-arrayexpress
TranscriptomicsMining gene expression data for low doses of radiation and pollutants (dioxin, toluene, formaldehyde)
Expression profiles of Drosophila melanogaster in response to ionizing radiation, formaldehyde, toluene, and 2,3,7,8-tetrachlorodibenzo-p-dioxin. RNA-seq analysis on 25,415 transcripts to measure the change in gene expression in males and females separately. An analysis of the genes unique to each ...
ORGANISM(S): Drosophila melanogaster 
2013-08-30 | E-GEOD-50377 | biostudies-arrayexpress
UnknownParent-child conversations associated with alcohol-related risk behaviours in young people (13-17 years) in the UK: a cross-sectional study.
Not available
S-EPMC7304640 | biostudies-literature
UnknownImproving health care from the bottom up: Factors for the successful implementation of kaizen in acute care hospitals.
Not available
S-EPMC8432859 | biostudies-literature
TranscriptomicsTranscription profiling of human EBV transformed cell lines established from patients with a novel immunodeficiency syndrome
Lysosome-related organelles have versatile functions including protein and lipid degradation, signal transduction, and protein secretion. The molecular elucidation of rare congenital diseases affecting endosomal/lysosomal biogenesis has given insights into physiological functions of the innate and a...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6322 | biostudies-arrayexpress
MetabolomicsGNPS - The nutritional and host environment shapes community ecology and keystone functions in a synthetic gut bacterial community
Microbe-microbe interactions are critical for gut microbiome function. A challenging task to understand health and disease-related microbiome signatures is to move beyond descriptive community-level profiling towards disentangling microbial interaction networks. Here, we aimed to determine members t...
ORGANISM(S): Bacteria (ncbitaxon:2) Mus Sp. (ncbitaxon:10095) 
2022-11-14 | MSV000090704 | GNPS
TranscriptomicsRNA-seq of wild-type, Pbx1/Pbx2 double-knockout and pMsgn1-mut EpiSCs differentiated in vitro to pre-somitic mesoderm in the first 24 hours of differentiation.
In vertebrates, body axis elongation is fuelled by bipotent neuromesodermal progenitors (NMPs), which support the development of both spinal cord and paraxial mesoderm (PM). HOX transcription factors have been historically implicated in axial elongation, with their sequential activation playing a fu...
ORGANISM(S): Mus musculus 
2021-07-21 | E-MTAB-9773 | biostudies-arrayexpress
UnknownT-cell recovery and evidence of persistent immune activation 12 months after severe COVID-19.
Not available
S-EPMC9347640 | biostudies-literature
UnknownEffect and Tolerance of N5 and N6 Chemotherapy Cycles in Combination with Dinutuximab Beta in Relapsed High-Risk Neuroblastoma Patients Who Failed at Least One Second-Line Therapy.
Not available
S-EPMC10341209 | biostudies-literature
TranscriptomicsImpact of Hells loss-of-function on DNA methylation in B cells during humoral immune responses: kinetic comparison of Mb1-Hells knockout and control mice by single-cell RNA sequencing
We are interested in deciphering the mechanism by which DNA methylation in late B cell differentiation affects humoral immune response. We chose to study a very rare immunodeficiency called ICF type 4, where a point mutation in a gene encoding the protein HELLS causes a lack of both circulating anti...
ORGANISM(S): Mus musculus 
2023-07-25 | E-MTAB-12499 | biostudies-arrayexpress
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