Sort   by:  
 Page size 
ProteomicsRadioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis
Antifibrotic therapy with nintedanib is the clinical mainstay in the treatment of progressive fibrosing interstitial lung disease (ILD). High-dimensional medical image analysis, known as radiomics, provides quantitative insights into organ-scale pathophysiology, generating digital disease fingerprin...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-17 | PXD052594 | Pride
Interstitial lung disease Radiomics Proteomics Multiomics Imaging Lung fibrosis Nintedanib 
TranscriptomicsTranscription profiling of neuroblastoma tumors with and without MYCN amplification
Purpose: Clinical courses of neuroblastomas (NBs) range from rapid progression with fatal outcome despite intensive multimodality therapies to spontaneous regression. Amplified MYCN oncogene defines a subgroup with poor outcome. However, a substantial number of MYCN single-copy NBs exhibits an aggre...
ORGANISM(S): Homo sapiens 
2007-06-01 | E-CVDE-2 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human neuroblastoma cells with and without MYCN oncogene induction and doxorubicin treatment
Purpose: Clinical courses of neuroblastomas (NBs) range from rapid progression with fatal outcome despite intensive multimodality therapies to spontaneous regression. Amplified MYCN oncogene defines a subgroup with poor outcome. However, a substantial number of MYCN single-copy NBs exhibits an aggre...
ORGANISM(S): Homo sapiens 
2007-06-01 | E-CVDE-3 | biostudies-arrayexpress
TranscriptomicsTranscription profling of human neuroblastoma samples to construct, validate and evalute a gene expression based classification of outcome of treatment
This set of 320 profiles was utilized to construct, validate and evaluate a gene-expression based classifier of outcome of neuroblastoma patients
ORGANISM(S): Homo sapiens 
2009-02-17 | E-TABM-38 | biostudies-arrayexpress
UnknownImproved discovery of RNA-binding protein binding sites in eCLIP data using DEWSeq.
Not available
S-EPMC10783507 | biostudies-literature
ProteomicsTumour mutations in long noncoding RNAs enhance cell fitness
Tumour DNA contains thousands of somatic single nucleotide variants (SNVs) in non-protein-coding elements, yet their functional significance remains poorly understood. Amongst the most highly mutated elements are long noncoding RNAs (lncRNAs), functional transcripts with known roles in carcinogenesi...
ORGANISM(S): Homo sapiens (Human) 
2023-07-20 | PXD034007 | Pride
Driver gene  cancer  long non-coding rnas 
ProteomicsDevelopment of a laser injury model using human cardiac spheroids
This study establishes a laser injury model using 3D cardiac spheroids composed of human induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) and cardiac fibroblasts (iPSC-CFs). Following the in vitro differentiation of both iPSC-CMs and iPSC-CFs, the two cell types are co-cultured to all...
ORGANISM(S): Homo sapiens (Human) 
2026-10-16 | PXD082285 | Pride
Laser ablation  microtissue  spheroid  injury  cardiac regeneration  fibrosis 
ProteomicsmtTF1: A Novel Factor Involved in Mitochondrial Gene Expression in Trypanosoma brucei
Project 20240909_20 mtRNAP IP BSF Project 20221209_BB mtRNAP IP PCF Mitochondrial DNA replication and gene expression are essential for cell survival. In Trypanosoma brucei, a protozoan animal and human parasite, the mitochondrial RNA polymerase (mtRNAP) plays roles in both transcription and DNA r...
ORGANISM(S): Trypanosoma brucei 
2026-10-19 | PXD066647 | Pride
Mitochondrial transcription Transcription factor Trypanosoma brucei Mitochondrial gene expression 
GenomicsGencode_550K
Lymphoma samples using HumanOmni
EGAD00010000949 | EGA
GenomicsGencode_15K
Lymphoma samples using CytoSNP
EGAD00010000947 | EGA
Sort   by:  
 Page size