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UnknownPhase II Intergroup Trial of Alisertib in Relapsed and Refractory Peripheral T-Cell Lymphoma and Transformed Mycosis Fungoides: SWOG 1108.
Not available
S-EPMC4500834 | biostudies-literature
UnknownM-CSF directs myeloid and NK cell differentiation to protect from CMV after HCT
Not available
S-SCDT-10_15252-EMMM_202317694 | biostudies-other
ProteomicsIgG-independent co-aggregation of FceRI and FcgRIIB results in LYN- and SHIP1-dependent tyrosine phosphorylation of FcgRIIB
We used tyrosine phosphorylation profiling by anti-pTyr-antibody mediated enrichment and subsequent analysis by mass spectrometry in order to determine the changes in early signalling after mast cell activation. Mast cells were stimulated with varying concentrations of antigen for one minute and the...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-17 | PXD009318 | Pride
Tyrosine phosphorylation Mouse Mast cell activation 
ProteomicsMetabolic Reprogramming Driven by Ant2 Deficiency Augments T Cell Function and Anti-Tumor Immunity
cell activation demands a significant boost in NAD+ levels, often outpacing the capacity of oxidative phosphorylation (OXPHOS). To explore how T cells manage this metabolic stress, we created T cell-specific ADP/ATP translocase-2 knockout (Ant2-/-) mice. Ant2, which is vital for ADP/ATP exchange bet...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-09 | PXD062646 | Pride
Naive t cells Mouse Ant2ko Spleen 
TranscriptomicsComplex in vivo RNA-seq analysis reveal reprogramming of Yersinia from virulent to persistent mode during infection [microarray II]
Whole transcriptome assessment of the Yersinia pseudotuberculosis strain YPIII grown under aerobic or anaerobic conditions to stationary phase. Y. pseudotuberculosis YPIII was grown at 25°C in LB medium supplemented with 10 g/l glucose and 0.2 M HEPES buffer under aeration or under anaerobic growth...
ORGANISM(S): Yersinia pseudotuberculosis YPIII 
2014-12-05 | E-GEOD-56476 | biostudies-arrayexpress
TranscriptomicsComplex in vivo RNA-seq analysis reveal reprogramming of Yersinia from virulent to persistent mode during infection [microarray I]
Whole transcriptome assessment of the Yersinia pseudotuberculosis strain YPIII grown under aerobic or anaerobic conditions to exponential phase. Y. pseudotuberculosis YPIII was grown at 25°C in LB medium supplemented with 10 g/l glucose and 0.2 M HEPES buffer under aeration or under anaerobic growt...
ORGANISM(S): Yersinia pseudotuberculosis YPIII 
2014-12-05 | E-GEOD-56475 | biostudies-arrayexpress
TranscriptomicsGeneration of organized anterior foregut epithelia from pluripotent stem cells using small molecules
Anterior foregut endoderm (AFE) gives rise to many tissue types of interest for therapeutic research including the esophagus, salivary glands, lung, thymus, parathyroid and thyroid. Despite its importance, only few reports describe the generation of AFE from pluripotent stem cells (PSCs) by directed...
ORGANISM(S): Mus musculus 
2013-04-15 | E-GEOD-42139 | biostudies-arrayexpress
TranscriptomicsAccumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae
To investigate the possible range of additional RNase P substrates in vivo a strand-specific, high-density microarray was used to analyze what RNA accumulates with a mutation in the catalytic RNA subunit of nuclear RNase P in Saccharomyces cerevisiae. A wide variety of noncoding RNAs were shown to a...
ORGANISM(S): Saccharomyces cerevisiae 
2011-08-29 | E-MEXP-3140 | biostudies-arrayexpress
TranscriptomicsAbsolute and induction TNF tolerance in primary human monocytes
The molecular basis of TNF tolerance is poorly understood. In this experiment, primary human monocytes were used to examine TNF refractoriness. We detect absolute tolerance as selective, dose-dependently affecting a small group of powerful effector molecules; induction tolerance represented a more ...
ORGANISM(S): Homo sapiens 
2014-02-11 | E-GEOD-45371 | biostudies-arrayexpress
MetabolomicsImpact of Diabetic Stress Conditions on Renal Cell Metabolome
Diabetic kidney disease is a major complication in diabetes mellitus, and the most common reason for end-stage renal disease. Patients suffering from diabetes mellitus encounter glomerular damage by basement membrane thickening, and develop albuminuria. Subsequently, albuminuria can deteriorate the ...
2019-10-08 | MTBLS1093 | MetaboLights
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