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TranscriptomicsHigh-fat diet induced gene expression changes in mouse retina may be prevented by introducing bilberries in diet
Obesity and diabetes associated visual impairment and vascular dysfunctions are increasing reasons for vision loss. The detailed mechanisms in these diseases are still largely unknown, but mice models have been useful to study these mechanisms and explore the detailed effects of potential compounds....
ORGANISM(S): Mus musculus 
2012-09-08 | E-GEOD-34154 | biostudies-arrayexpress
TranscriptomicsBilberries reduce low-grade inflammation and subacute endotoxemia in individuals with features of metabolic syndrome - microarray/QPCR profiling of dietary effects of bilberries in PBMCs
Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. The most diverse source of dietary anti-inflammatory compounds is polyphenols and especially anthocyanins, which are major polyphenols in bilberries (Vaccinium myrtillus). We investigated the effec...
ORGANISM(S): Homo sapiens 
2012-09-15 | E-GEOD-34145 | biostudies-arrayexpress
ProteomicsSystems toxicological assessment of the mentholated Tobacco Heating System 2.2 product revealed reduced cellular and molecular exposure effects compared to cigarette smoke [quantitative proteomics of rat nasal epithelium]
Aiming to reduce smoking-related health risks, potential reduced risk products (pRRPs) are being developed. The Tobacco Heating System (THS) 2.2 is a recently developed pRRP, which utilizes the heat-not-burn principle. In this study, systems toxicology approaches were engaged to assess the respirato...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-13 | PXD003591 | Pride
Reduced risk tobacco product  systems toxicology  rat inhalation study  itraq 
ProteomicsSystems toxicological assessment of the mentholated Tobacco Heating System 2.2 product revealed reduced cellular and molecular exposure effects compared to cigarette smoke [quantitative proteomics of lung tissue]
Aiming to reduce smoking-related health risks, potential reduced risk products (pRRPs) are being developed. The Tobacco Heating System (THS) 2.2 is a recently developed pRRP, which utilizes the heat-not-burn principle. In this study, systems toxicology approaches were engaged to assess the respirato...
ORGANISM(S): Rattus norvegicus (Rat) 
2016-12-12 | PXD003580 | Pride
Reduced risk tobacco product  systems toxicology  rat inhalation study  itraq 
ProteomicsSystems toxicology assessment of CHTP1.2 [Lung Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008422 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [Liver Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008423 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
ProteomicsSystems toxicology assessment of CHTP1.2 [RNE Data]
Modified risk tobacco products (MRTPs) have the potential to reduce smoking-related health risks. The Carbon Heated Tobacco Product 1.2 (CHTP1.2) is a potential MRTP that uses a pressed carbon heat source to generate an aerosol by heating tobacco. This study reports the results from the systems toxi...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-03-19 | PXD008424 | Pride
Rat Mrtp Itraq Lc-msms Systems toxicology 
TranscriptomicsInterior spruce_Bark_Leptographium abietinum_inoculation
Using 21K spruce microarray (that contains 21.8 thousand unique transcripts) we performed analysis of the transcriptome response of interior spruce (Picea glauca x engelmannii) inoculated with the spruce beetle (Dendroctonus rufipennis) vectored blue stain fungal pathogen Leptographium abietinum or ...
ORGANISM(S): Picea engelmannii x Picea glauca 
2012-12-01 | E-GEOD-23678 | biostudies-arrayexpress
UnknownA multi-omic approach implicates novel protein dysregulation in post-traumatic stress disorder.
Not available
S-EPMC12042318 | biostudies-literature
UnknownEpigenome-wide association studies identify novel DNA methylation sites associated with PTSD: a meta-analysis of 23 military and civilian cohorts.
Not available
S-EPMC11658418 | biostudies-literature
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