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UnknownAmicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Not available
S-EPMC4253140 | biostudies-literature
UnknownEducation-related variation in coronary procedure rates and the contribution of private health care in Australia: a prospective cohort study.
Not available
S-EPMC7427777 | biostudies-literature
TranscriptomicsMapping and dynamics of regulatory DNA and transcription factor networks in A. thaliana
We mapped DNaseI hypersensitive sites (DHSs) and applied genomic footprinting to define in vivo transcription factor (TF) occupancy at nucleotide resolution across the A. thaliana genome in whole seedlings during heat- and light-response states. We find that trait-associated variation localizes with...
ORGANISM(S): Arabidopsis thaliana 
2013-12-15 | E-GEOD-53322 | biostudies-arrayexpress
TranscriptomicsBlood Gene Expression Profiling of an Early Acetaminophen Response (II)
Acetaminophen can adversely affect the liver especially when overdosed. We used whole blood as a surrogate to identify genes as potential early indicators of an acetaminophen-induced response. In a clinical study, healthy human subjects were dosed daily with 4g of either acetaminophen or placebo p...
ORGANISM(S): Homo sapiens 
2016-02-16 | E-GEOD-70786 | biostudies-arrayexpress
UnknownA 5-hydroxymethylcytosine-based noninvasive model for acute myocardial infarction in type 2 diabetes: implications in cardiovascular outcomes from a 5-year median follow-up study.
Not available
S-EPMC12934080 | biostudies-literature
TranscriptomicsDeep sequencing the circadian and light-dependent transcriptome of Drosophila brain
Eukaryotic circadian clocks include transcriptional/translational feedback loops that drive 24-hour rhythms of transcription.These transcriptional rhythms underlie oscillations of protein abundance, thereby mediating circadian rhythms of behavior, physiology, and metabolism. Numerous studies over th...
ORGANISM(S): Drosophila melanogaster 
2012-03-27 | E-GEOD-36108 | biostudies-arrayexpress
TranscriptomicsJnk1 in murine hepatic stellate cells is a crucial mediator of liver fibrogenesis
Hepatic fibrosis is a wound-healing response to chronic liver injury, which may result in cirrhosis and liver failure. The c-Jun N-terminal kinase-1 (JNK1) gene has been shown to be involved in liver fibrosis. Here, we aimed to investigate the molecular mechanism and identify the cell-type involved ...
ORGANISM(S): Mus musculus 
2013-11-27 | E-GEOD-40041 | biostudies-arrayexpress
TranscriptomicsDeep sequencing the circadian transcriptome of Drosophila brain
RNAseq transcriptional profiling of Drosophila brains from wildtype, and period loss-of-function animals with time points taken over two days. 2 days of brain collection, time points at ZT0, ZT6, ZT12, and ZT18; wildtype and per0 flies. 10-12 brains per time point.
ORGANISM(S): Drosophila melanogaster 
2012-01-01 | E-GEOD-29972 | biostudies-arrayexpress
TranscriptomicsAge-specific variation in immune response in Drosophila melanogaster has a genetic basis.
Immunosenescence, the age-related decline in immune system function, is a general hallmark of aging. While much is known about the cellular and physiological changes that accompany immunosenescence, we know very little about the genetic influences on this phenomenon. We used microarrays to determin...
ORGANISM(S): Drosophila melanogaster 
2012-05-02 | E-GEOD-37708 | biostudies-arrayexpress
Transcriptomicscircadian clock in cartilage
This experiment investigated the circadian clock in mice cartilage. A microarray time-series was performed using xiphoid tissue (metasternum) from mice in constant darkness. Time points were every 4 hr for 40 hr in total.
ORGANISM(S): Mus musculus 
2013-10-19 | E-MEXP-3780 | biostudies-arrayexpress
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