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GenomicsWhole-genome nucleosome mapping in meiotic diploid S. cerevisiae
We determined nucleosome positions throughout the genome in diploid S. cerevisiae undergoing early stages of synchronous meiosis. This study sought to assess if systematic reorganization of nucleosomes occurs during meiotic prophase at or near sites of DNA double strand break formation. Six samples ...
ORGANISM(S): Saccharomyces cerevisiae 
2011-03-07 | E-GEOD-26452 | biostudies-arrayexpress
MetabolomicsA serum nuclear magnetic resonance-based metabolomic signature of antiphospholipid syndrome
Antiphospholipid syndrome (APS) is a rheumatic inflammatory chronic autoimmune disease inducing hypercoagulable state associated with vascular thrombosis and pregnancy loss in women. Cardiac, cerebral and vascular strokes in these patients are responsible for reduction in life expectancy. Timely dia...
2017-09-06 | MTBLS356 | MetaboLights
ProteomicsStress granules proteome composition
Analysis of stress granules in HeLa cells, after exposure to different stimuli. Granules were collected by a newly devised enrichment method, described in manuscript. Proteomics sample preparation of granules was carried out using the Single-pot, solid phase-enhanced sample preparation, SP3 method (...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-02 | MSV000090634 | MassIVE
UnknownRapid and accurate large-scale genotyping of duplicated genes and discovery of interlocus gene conversions.
Not available
S-EPMC3985568 | biostudies-literature
TranscriptomicsTranscription profiling of human osteosarcoma derived cell lines treated with decitabine
Background: Epigenetic modifications such as methylation silencing of genes with CpG-island-associated promoters is frequently observed in cancer. Studies regarding the implications of epigenetic modifications in osteosarcoma (OS) have been limited. The epigenetic drug decitabine is a potential r...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7454 | biostudies-arrayexpress
ProteomicsABCB5+ limbal epithelial stem cells inhibit developmental, but promote inflammatory (lymph)angiogenesis while preventing corneal inflammation
ABCB5 is marker for Limbal epithilal stem cells. A comparison between ABCB5+ versus ABCB5- cultured human limbal epithelial cells was carried out to evaluate the properties of the limbal stem cell ABCB5+ with a special focus on their role in inflammation and angiogenesis.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041004 | Pride
(lymph)angiogenesis Cornea Abcb5 Limbal epithelial stem cells 
UnknownThe population genetics of human disease: The case of recessive, lethal mutations.
Not available
S-EPMC5619689 | biostudies-literature
UnknownTwo steps forward, one step back: determining XPD helicase mechanism by single-molecule fluorescence and high-resolution optical tweezers.
Not available
S-EPMC4295835 | biostudies-literature
UnknownStructural basis of highly conserved ribosome recycling in eukaryotes and archaea.
Not available
S-EPMC6878762 | biostudies-literature
UnknownDisruptive CHD8 mutations define a subtype of autism early in development.
Not available
S-EPMC4136921 | biostudies-literature
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