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MetabolomicsRANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies

INTRODUCTION: The Metabolomics Standards Initiative has recommended four categories for metabolite assignments in NMR-based metabolic profiling studies. The putatively annotated compound category is most commonly reported by metabolomics investigators. However, there is significa...

2019-09-27 | MTBLS781 | MetaboLights
ProteomicsSelective Inhibition of MTHFD1/2 in T Cells from Patients with Rheumatoid Arthritis
Ex vivo T cell treatment Immunomagnetic negative isolation was used to obtain untouched human T cells from previously frozen PBMC samples of treatment-naïve (n=6) and MTX-IR (n=3) RA patients (Table S1). The isolated T cells were then cultured and stimulated in a 96-well round-bottom plates for susp...
ORGANISM(S): Homo sapiens (Human) 
2026-04-02 | PXD061849 | Pride
Proteomics Methotrexate Selective mthfd1/2 inhibitor T cells Rheumatoid arthritis 
UnknownRegulatory T Cells in Tumor-Associated Tertiary Lymphoid Structures Suppress Anti-tumor T Cell Responses.
Not available
S-EPMC4826619 | biostudies-literature
ProteomicsIdentification of the MuRF1 skeletal muscle ubiquitylome through quantitative proteomics
MuRF1 is a muscle-specific E3 ubiquitin ligase and component of the ubiquitin proteasome system. MuRF1 is transcriptionally upregulated under conditions that cause muscle loss, in both rodents and humans, and is a recognized marker of muscle atrophy. In this study, we used in vivo electroporation ...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-07 | PXD023872 | Pride
Ubiquitin proteomics Muscle atrophy Murf1 Protein degradation Electroporation 
UnknownInhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling.
Not available
S-EPMC2397475 | biostudies-literature
UnknownZAP-70: an essential kinase in T-cell signaling.
Not available
S-EPMC2857167 | biostudies-literature
UnknownEngineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy.
Not available
S-EPMC6173196 | biostudies-literature
UnknownSuperresolution fluorescence imaging of mitochondrial nucleoids reveals their spatial range, limits, and membrane interaction.
Not available
S-EPMC3233019 | biostudies-literature
UnknownEscherichia coli SymE is a DNA-binding protein that can condense the nucleoid.
Not available
S-EPMC9018529 | biostudies-literature
UnknownThe Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries.
Not available
S-EPMC8363055 | biostudies-literature
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