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ProteomicsGestational age-dependent proteome changes in amniotic fluid extracellular vesicles
This study isolated and analysed extracellular vesicles from human amniotic fluid derived from routine second-trimester amniocentesis and elective Caesarean section at term. Label-free proteomics identified 4137 proteins with high confidence.
ORGANISM(S): Homo sapiens (Human) 
2025-06-23 | PXD058882 | Pride
Human Extracellular vesicles Amniotic fluid 
TranscriptomicsThe amniotic fluid transcriptome: a source of novel information about human fetal development
Amniotic fluid (AF) is a complex biological material that provides a unique window into the developing human. Residual AF supernatant contains cell-free fetal RNA. The objective of this study was to develop an understanding of the AF core transcriptome by identifying the transcripts ubiquitously pre...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33168 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome [Set 2]
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-47393 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome [Set 1]
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-47392 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-47394 | biostudies-arrayexpress
MetabolomicsFatal COVID-19 pulmonary disease involves ferroptosis.

SARS-CoV-2 infection causes severe pulmonary manifestations, with poorly understood mechanisms and limited treatment options. Hyperferritinemia and disrupted lung iron homeostasis in COVID-19 patients imply that ferroptosis, an iron-dependent cell death, may occur. Immunostaining and lipidomic an...

2024-07-11 | MTBLS3107 | MetaboLights
TranscriptomicsRNA-Seq and expression microarray highlight different aspects of the fetal amniotic fluid transcriptome [RNA-Seq]
The second trimester fetal transcriptome can be assessed based on cell-free RNA found within the amniotic fluid supernatant. The objective of this study was to compare the suitability of two technologies for profiling the human fetal transcriptome: RNA-Seq and expression microarray. Comparisons were...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-49890 | biostudies-arrayexpress
TranscriptomicsRNA-Seq and expression microarray highlight different aspects of the fetal amniotic fluid transcriptome [microarray]
The second trimester fetal transcriptome can be assessed based on cell-free RNA found within the amniotic fluid supernatant. The objective of this study was to compare the suitability of two technologies for profiling the human fetal transcriptome: RNA-Seq and expression microarray. Comparisons were...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-49891 | biostudies-arrayexpress
TranscriptomicsGlobal Gene Expression Analysis of Term Amniotic Fluid Cell-Free Fetal RNA
The objective of this study was to identify the tissue expression patterns and biological pathways enriched in term amniotic fluid cell-free fetal RNA by comparing functional genomic analyses of term and second-trimester amniotic fluid supernatants. There were 2,871 significantly differentially regu...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-46286 | biostudies-arrayexpress
TranscriptomicsMaternal obesity affects fetal neurodevelopmental and metabolic gene expression
To investigate fetal gene expression in obese compared to lean women in the second trimester, by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from obese cases and lean controls revealed differential expression of 205 genes. Functional analys...
ORGANISM(S): Homo sapiens 
2013-07-04 | E-GEOD-48521 | biostudies-arrayexpress
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