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TranscriptomicsA mesenchymal stromal cell gene signature for donor age
Human aging is associated with loss of function and regenerative capacity. Human bone marrow derived mesenchymal stromal cells (hMSCs) are involved in tissue regeneration, evidenced by their capacity to differentiate into several lineages and therefore are considered the gold standard for cell-based...
ORGANISM(S): Homo sapiens 
2012-07-20 | E-GEOD-39540 | biostudies-arrayexpress
UnknownDeciphering Cattle Temperament Measures Derived From a Four-Platform Standing Scale Using Genetic Factor Analytic Modeling.
Not available
S-EPMC7304504 | biostudies-literature
TranscriptomicsTranscription profiling of pre-injected brain cells from female INK4a/ARF knock-out, BMI1 INK4a/ARF knock-out mice and tumor cells derived from these mice
Comparison of gene expression profiles between pre-injected brain cells from female INK4a/ARF knock-out, BMI1 INK4a/ARF knock-out mice and tumor cells derived thereof.
ORGANISM(S): Mus musculus 
2007-11-15 | E-NCMF-4 | biostudies-arrayexpress
TranscriptomicsFunctional Identification of Critical Bmi1 target genes in Neural Progenitor and Malignant Glioma cells
In this study, we combined a genome-wide analysis of the Polycomb protein Bmi1 and an in vivo RNAi screening to identify critical targets whose repression in neural progenitor and Malignant Glioma cells enables normal and aberrant self-renewal. Bmi1 ChIP-sequencing generated in 2 primary adult mouse...
ORGANISM(S): Mus musculus 
2013-05-21 | E-GEOD-33912 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse neural stem cells derived from Ink4a/Arf-/- vs Bmi1-/-;Ink4a/Arf-/- mutants
Comparison of gene expression of Ink4a/Arf-/- vs Bmi1-/-;Ink4a/Arf-/- subventricular zone (SVZ) derived mouse neural stem cells (NSC) on Laminin (LM) and Fibronectin (FN) substrates.
ORGANISM(S): Mus musculus 
2009-02-25 | E-NCMF-22 | biostudies-arrayexpress
UnknownUnbiased Quantitative Models of Protein Translation Derived from Ribosome Profiling Data.
Not available
S-EPMC4537299 | biostudies-literature
TranscriptomicsPredicting the therapeutic efficacy of MSC in bone tissue engineering using the molecular marker CADM1
Mesenchymal stromal cells (hMSCs) are advancing into the clinic but the therapeutic efficacy of hMSCs faces the problem of donor variability. In bone tissue engineering, no reliable markers have been identified which are able to predict the bone-forming capacity of hMSCs prior to implantation. To th...
ORGANISM(S): Homo sapiens 
2018-10-04 | E-MTAB-7210 | biostudies-arrayexpress
TranscriptomicsQuantitative Analysis by Next Generation Sequencing of LSK (Lin- Sca1+ cKit+) hematopoietic progenitors and splenic B cells (naive and in vitro LPS activated) transcriptomes from Wild Type and Usp3-/- mice
Purpose: the goal of this study is to investigate the consequences of USP3 deletion on gene expression in mouse LSK hematopoietic progenitors and in splenic B cells Methods: mRNA profiles of 8 weeks-old wild-type (WT) and ubiquitin specific protease 3 knockout (Usp3−/−) mice were generated by deep ...
ORGANISM(S): Mus musculus 
2014-07-24 | E-GEOD-58495 | biostudies-arrayexpress
UnknownHi-C Chromatin Interaction Networks Predict Co-expression in the Mouse Cortex.
Not available
S-EPMC4429121 | biostudies-literature
UnknownNeuropsychological Test Performance of Cognitively Healthy Centenarians: Normative Data From the Dutch 100-Plus Study.
Not available
S-EPMC7379661 | biostudies-literature
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