Human airway epithelial cell line

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Transcriptomics (232)
Unknown (224)
Genomics (76)
Proteomics (33)
Other (3)
Metabolomics (1)

Organisms

Homo sapiens (189)
Mus musculus (54)
Schizophyllum commune H4-8 (26)
Mycobacterium tuberculosis SP7 (26)
Oryza sativa Japonica Group (26)
Candidatus Endoriftia persephonae (26)
Mycobacterium tuberculosis SP10 (26)
Mycobacterium tuberculosis SP13 (26)
Mycobacterium tuberculosis SP22 (26)
Enterobacter ludwigii (26)
Chlamydomonas reinhardtii (26)
Lama (26)
Pyricularia oryzae P131 (26)
Rattus norvegicus (4)
Drosophila melanogaster (3)
Aspergillus fumigatus (3)
Sus scrofa (3)
Helicobacter pylori (2)
Bos taurus (2)
Canis lupus familiaris (2)
Arabidopsis thaliana (2)
Aspergillus flavus (1)
Capra hircus (1)
Brassica napus (1)
Neisseria meningitidis (1)
Zea mays (1)
mixed sample (1)
Hordeum vulgare (1)
Saccharomyces cerevisiae (1)
Macaca mulatta (1)

Organisms

Homo sapiens (40)
Aspergillus fumigatus (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (233)
ENA (48)
geo (33)
pride (26)
EGA (1)
iProX (1)
jPOST (1)
MassIVE (1)
MetaboLights (1)

Tissue

Epithelial cell (16)
Cell culture (13)
Lung (4)
Bronchial epithelial cell line (1)
Nasal epithelium cell line (1)
Lung cell line (1)
Nasal mucosa (1)
Respiratory epithelial cell (1)
Bronchial epithelial cell (1)
Epithelial cell of lung (1)
Sputum (1)

Disease

Cystic fibrosis (4)
Respiratory syncytial virus infectious disease (2)
FRD1234 (1)
Perilobar nephrogenic rest (1)
Post-stasis (1)
Xenografts with H1299 cell line (1)
Prostate cancer (1)
Carcinoma (1)
Normal (1)
Asthma (1)
Severe acute respiratory syndrome (1)
COVID-19 (1)

Technology Type

Mass Spectrometry (26)
Shotgun proteomics (13)
Bottom-up proteomics (6)
Data-dependent acquisition (4)
Data-independent acquisition (2)
SWATH MS (2)
Mass spectrometry (1)
Top-down proteomics (1)
Affinity purification coupled with mass spectrometry proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (19)
Illumina HiSeq 2500 (7)
Illumina HiSeq 2000 (7)
NextSeq 500 (7)
Illumina Genome Analyzer IIx (3)
Illumina HiSeq 4000 (3)
Element AVITI (2)
N/A (2)
NextSeq 2000 (2)
Bravo automated liquid handling robot station (Agilent) (1)
RNA Qubit (Invitrogen Q32852) (1)
Zymo Quick-RNA Microprep Kit (Zymo Research R1051) (1)
12-well plates (Sarstedt 83.3921), 24-Well Plates (1)
Next GEM Single Cell 3' Gel Bead kit v3.1 (1)
Chromium Nuclei Isolation kit (10x Genomics 1000493) (1)
10X Genomics Chromium (1)
Axon Instruments GenePix 4000B scanner (1)
Computater Servers UPPMAX-SNIC. (1)
Illumina Tru-seq RNA (1)
NanoDrop spectrophotometer (NanoDrop Technologies, Wilmington, DE) (1)
Dynamic light scattering and zeta potential. The experiments were performed on a Malvern Zetasizer NanoZS instrument using a He-Ne laser (Max, 5 mW) at 633 nm. (1)
454 GS 20 (1)
Scanning hardware (1)
Illumina NovaSeq X (1)
Illumina HiSeq 1000 (1)
MinION (1)
Illumina NextSeq 500 (1)
Illumina MiSeq (1)
NextSeq 550 (1)
Illumina HiSeq 3000 (1)

Publication Date

2012 (27)
2011 (26)
2014 (25)
2013 (23)
2023 (20)
2015 (19)
2010 (18)
2022 (17)
2020 (16)
2026 (15)
2016 (14)
2025 (12)
2008 (12)
2024 (11)
2021 (8)
2009 (7)
2007 (7)
2019 (6)
2018 (5)
2006 (5)
2004 (2)
2017 (1)

CHEBI ID

CHEBI:68440 (1)
CHEBI:155898 (1)
CHEBI:28800 (1)
CHEBI:89930 (1)
CHEBI:16283 (1)
CHEBI:15603 (1)
CHEBI:27470 (1)
CHEBI:17780 (1)
CHEBI:15971 (1)
CHEBI:16977 (1)
CHEBI:17196 (1)
CHEBI:17295 (1)
CHEBI:17115 (1)
CHEBI:36313 (1)
CHEBI:15428 (1)
CHEBI:17895 (1)
CHEBI:18019 (1)
CHEBI:16015 (1)
CHEBI:18050 (1)
CHEBI:15760 (1)
CHEBI:16709 (1)
CHEBI:74795 (1)
CHEBI:16467 (1)
CHEBI:7916 (1)
CHEBI:17750 (1)
CHEBI:27897 (1)
CHEBI:17154 (1)
CHEBI:16946 (1)
CHEBI:18183 (1)
CHEBI:17203 (1)

Metabolite Name

2-Methylnicotinamide (1)
L-Cysteinylglycine disulfide (1)
Prolylphenylalanine (1)
Asymmetric dimethylarginine (1)
N-Acetylgalactosamine (1)
1-[(5-Amino-5-carboxypentyl)amino]-1-deoxyfructose (1)
L-Cystine (1)
L-Kynurenine (1)
Pyroglutamic acid (1)
L-Leucine (1)
5-Hydroxy-L-tryptophan (1)
Methionine sulfoxide (1)
L-Methionine (1)
L-Histidine (1)
L-Alanine (1)
L-Asparagine (1)
Glycine (1)
L-Threonine (1)
L-Serine (1)
L-Phenylalanine (1)
L-Glutamic acid (1)
L-Tyrosine (1)
Glycerophosphocholine (1)
L-Glutamine (1)
Pyridoxine (1)
L-Arginine (1)
Pantothenic acid (1)
Tryptophan (1)
Betaine (1)
Niacinamide (1)

First Public Date

2023 (9)
2024 (7)
2020 (7)
2014 (7)
2026 (5)
2021 (3)
2019 (2)
2018 (2)
2015 (2)
2022 (1)
2017 (1)
2016 (1)
2013 (1)

Classification

fungi (1)

Study type

Transcription profiling by array (109)
RNA-seq of coding RNA (25)
ChIP-seq (18)
RNA-seq of coding RNA from single cells (15)
Methylation profiling by array (9)
Other (7)
RNA-seq of non coding RNA (6)
Comparative genomic hybridization by array (5)
ChIP-chip by array (4)
Proteomic profiling by array (4)
ChIP-chip by tiling array (3)
Genotyping by array (3)
RNA-seq of total RNA (3)
Cell line - One-color microarray (2)
Cell line - High-throughput sequencing (2)
Transcription profiling by RT-PCR (2)
ATAC-seq (2)
Single nucleus RNA sequencing (2)
MicroRNA profiling by array (2)
DNA-seq (2)
Methylation profiling by high throughput sequencing (2)
GRO-seq (1)
Cell line - Single-cell sequencing (1)
Unknown experiment type (1)
RNA-seq of non coding RNA from single cells (1)
Transcription profiling by tiling array (1)
RIP-seq (1)

Release Date

2012 (37)
2015 (34)
2023 (32)
2014 (32)
2020 (31)
2011 (29)
2013 (28)
2022 (27)
2021 (25)
2024 (23)
2016 (23)
2010 (22)
2025 (17)
2019 (16)
2008 (16)
2018 (14)
2017 (13)
2026 (10)
2009 (9)
2007 (9)
2006 (5)
2004 (2)
2005 (2)
1998 (1)

Lab affiliation

Karolinska Institutet (2)
Department of Virology and Immunology, Institute of Microbiology and Biotechnology, Maria Curie-Sklodowska University in Lublin, Poland (1)
Molecular and Integrative Cystic Fibrosis (miCF) Research Laboratory, School of Women’s and Children’s Health, UNSW Medicine, UNSW Sydney (lab head) (1)
Cambridge Institute of Therapeutic Immunology and Infectious Disease Jeffrey Cheah Biomedical Centre Cambridge Biomedical Campus Puddicombe Way Cambridge CB2 OAW (1)
Paul J Lehner PhD FRCP FMed Sci Professor of Immunology and Medicine Wellcome Trust Principal Research Fellow Honorary Consultant Infectious Diseases Cambridge Institute of Therapeutic Immunology and Infectious Disease Jeffrey Cheah Biomedical Centre Cambridge Biomedical Campus Puddicombe Way Cambridge CB2 OAW (1)
Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charite ‐ Universitatsmedizin, Germany; German Center for Lung Research (DZL), Associated Partner Site, Germany; Berlin Institute of Health (BIH) at Charité - Universitätsmedizin Berlin, Germa (1)
Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, 792 Elizabeth St, Melbourne, 3000, Victoria, Australia. (1)
Department of Microgravity and Translational Regenerative Medicine, Otto-von-Guericke University Magdeburg, Universitätsplatz 2, 39106 Magdeburg, Germany (1)
Division of Immunobiology, Cincinnati Children’s Hospital, Cincinnati, OH Department of Pediatrics, University of Cincinnati, Cincinnati OH Correspondence: (1)
Science for Life Laboratory; Department of Oncology Pathology, Karolinska Institute, Stockholm, Sweden (1)
Institute for Infectious Diseases, Faculty of Medicine, University of Bern, Bern, Switzerland (1)
Respiratory and Emerging Viruses group Department of Infection Biology Institute of Infection and Global Health, University of Liverpool (1)
Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford, OX1 3RE (1)
University of Oklahoma Health Sciences Center (1)
Department of Oncology and Pathology, Karolinska Institute and Science for Life Laboratory (1)
Weill Institute for Cell and Molecular Biology, Department of Computational Biology, Cornell University (1)
Molecular and Integrative Cystic Fibrosis (miCF) Research Laboratory, School of Women’s and Children’s Health, UNSW Medicine, UNSW Sydney (1)
Institute of Lung Health and Immunity and Comprehensive Pneumology Center with the CPC-M BioArchive, Helmholtz Zentrum München, Member of the German Center of Lung Research (DZL) - München (Germany) (1)
Sun yat-sen university (1)
Centre for Proteome Research, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK (1)
Professor Cellular and Molecular Medicine Department University of Arizona College of Medicine - Tucson (1)
Baxter Laboratory for Stem Cell Biology Department of Microbiology & Immunology Stanford University School of Medicine 269 Campus Drive Stanford, CA 94305-5175, USA (1)
Associate Professor, Department of Biochemistry & Molecular Biology, UTMB Mass Spectrometry Director, University of Texas Medical Branch – Galveston, Texas, USA (1)
Chair in Infection and Global Health, Department of Infection Biology, Institute of Infection and Global Health, University of Liverpool, (1)
Analytical Chemistry Lab, Istituto Italiano di Tecnologia, Via Morego 30, 16163, Genova, Italy (1)

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Human CA2 ES cells undergoing stepwise differentiation to airway epithelium and challenged with TNFa and LPS

This study examines the innate immune response of human pluripotent stem cell derived airway epithelium. Immune challenge was performed with TNF-alpha or bacterial lipopolysaccharide (LPS) Airway epithelium differentiated from the ES line CA2 was compared to paired differentiated cells stimulated wi...

ORGANISM(S): Homo sapiens

2014-10-01 | E-GEOD-59472 | biostudies-arrayexpress

Fungal allergen extracts-induced gene expression in airway epithelial cells (NCI-H292)

We compared the gene expression stimulated with fungal extracts from Aspergillus (A.) fumigatus, Alternaria (A.) alternata, or Penicillium (P.) notatum in NCI-H292 (a human bronchial epithelial cell line) to search Allergic bronchopulmonary mycosis (ABPM)-related genes. We identified a mucin-related...

ORGANISM(S): Homo sapiens

2011-07-07 | E-GEOD-22323 | biostudies-arrayexpress

Transcription profiling of human bronchial airway epithelial cells infected with P. aeruginosa, S.aureus or respiratory syncytial virus vs uninfected controls to investigate the role of epithelial cells upon infection of airway pathogens

Bronchial epithelial cells represent the first line of defense against invading airborne pathogens. They are important contributors to innate mucosal immunity and provide a variety of anti-microbial effectors. To investigate the role of epithelial cells upon infection of airway pathogens, we stimula...

ORGANISM(S): Homo sapiens

2007-11-11 | E-GEOD-6802 | biostudies-arrayexpress

Phospho-proteomic analysis of IL-13 treated human airway epithelial cell line (A549)

Allergic asthma is a chronic inflammatory airway disease driven by the cytokine interleukin-13 (IL-13). Although IL-13 signals through the canonical JAK1/TYK2/STAT6 pathway, our understanding of the totality of IL-13-induced signaling intermediates is incomplete. To address this, we performed an unb...

ORGANISM(S): Homo sapiens (Human)

2025-12-05 | PXD066489 | Pride

Characterization of the roles of the RNA-binding protein AUF-1 in airway epithelial inflammatory responses

The RNA-binding protein AU-rich-element factor-1 (AUF-1) regulates mRNA decay and translation of genes during inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD). Decreased AUF-1 expression was described in bronchiolar epithelium of COPD pa...

ORGANISM(S): Homo sapiens

2023-04-14 | E-MTAB-12583 | biostudies-arrayexpress

mRNA-seq of Human Airway Epithelial Cells

mRNA expression was profiled from pooled bronchial airway epithelial cell brushings (n=3 patients/pool) obtained during bronchoscopy from healthy never (NS) and current smokers (S) and smokers with (C) and without (NC) lung cancer 4 samples were sequened, each representing a pool of 3 patients. The...

ORGANISM(S): Homo sapiens

2011-06-01 | E-GEOD-29006 | biostudies-arrayexpress

Infection of the larval airway epithelium by Erwinia carotovora

The unsurpassed simplicity of the fruitflyâ€™s airway epithelium, that is made of homogenous epithelial cells only, favours its use as a model to study general features and response characteristics of airway epithelia in general. All epithelial cells are able to launch an immune response as characte...

ORGANISM(S): Drosophila melanogaster

2010-05-19 | E-GEOD-11444 | biostudies-arrayexpress

Functional genomics of human bronchial epithelial cells interacting with conidiospores of Aspergillus fumigatus

The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and in asthma pathogenesis. These cells are constantly exposed to conidiospores of the ubiquitous mould Aspergillus fumigatus, which are small enough to reach the alveoli. This exposure is asymptomatic in mo...

ORGANISM(S): Homo sapiens

2011-06-01 | E-GEOD-16628 | biostudies-arrayexpress

The response of human primary airway epithelial cells to Influenza or RSV infection [hAECs_Agilent].

To investigate how human airway epithelial cells respond to Influenza or RSV infection, we harvested airway epithelial cells from the mainstream bronchi of human donors and cultured them as previously described (Pickles et al,1998) in a polarized system that resembles the in vivo mucociliary pseudo...

ORGANISM(S): Homo sapiens

2012-03-12 | E-GEOD-32138 | biostudies-arrayexpress

The response of human primary airway epithelial cells to Influenza or RSV infection [hAECs_Illumina]

ORGANISM(S): Homo sapiens

2012-03-12 | E-GEOD-32139 | biostudies-arrayexpress

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569 Results

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