Sort   by:  
 Page size 
MetabolomicsSpatiotemporal determination of metabolite activities in the corneal epithelium on a chip
The corneal epithelial barrier maintains the metabolic activities of the ocular surface by regulating membrane transporters and metabolic enzymes responsible for the homeostasis of the eye as well as the pharmacokinetic behavior of drugs. Despite its importance, no established biomimetic in vitro me...
2021-07-13 | MTBLS2274 | MetaboLights
ProteomicsProteomic profiling of human corneal epithelial cells under hyperosmotic stress
This project compared the proteomic change between human corneal epithelial cells cultured under hyperosmotic and isosmotic condition. This aimed to reveal differentially expressed proteins that was associated with osmoregulation in human corneal epithelial cells.
ORGANISM(S): Homo Sapiens (human) 
2025-05-14 | PXD054330 | JPOST Repository
TranscriptomicsGene expression profile of the SV40-immortalized human corneal epithelial cells
Microarray was used to study global gene expression of a cell culture model based on SV40-immortalized human corneal epithelial (iHCE) cells. The gene expression profile of the cell line was compared to the normal human corneal epithelium. Affymetrix HG-U133A GeneChips® were used for microarray exp...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-22539 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of PNN- and ESRP1-regulation in Human Corneal Epithelial Cells
Pnn depletion in developing mouse corneal epithelium led to disrupted alternative splicing of multiple ESRP-regulated epithelial-type exons. In human corneal epithelial cells (HCET), ESRP1 and PNN displayed close localization in and around nuclear speckles and their physical association in protein c...
ORGANISM(S): Homo sapiens 
2013-01-24 | E-GEOD-41996 | biostudies-arrayexpress
TranscriptomicsHuman Corneal Epithelial Cells (hTCEpi) 6h Treatment with 100nM Vitamin D (1,25D3) vs. Vehicle Control
Inflammatory signals must be regulated and kept in check in order to prevent tissue damage. This is especially true in the cornea, where damage can induce loss of transparency, essential for vision. Toll-like receptors (TLRs) are present at the ocular surface and, in addition to being protective a...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-72662 | biostudies-arrayexpress
TranscriptomicsHuman Corneal Epithelial Cells (SV40-HCEC) 6h Treatment with 100nM Vitamin D (1,25D3) vs. Vehicle Control
Inflammatory signals must be regulated and kept in check in order to prevent tissue damage.  This is especially true in the cornea, where damage can induce loss of transparency, essential for vision.  Toll-like receptors (TLRs) are present at the ocular surface and, in addition to being protective...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-72663 | biostudies-arrayexpress
TranscriptomicsMicroRNA-145 Regulates Human Corneal Epithelial Differentiation
This SuperSeries is composed of the following subset Series: GSE24979: MicroRNA-145 Regulates Human Corneal Epithelial Differentiation [Agilent-016436 array data] GSE24980: MicroRNA-145 Regulates Human Corneal Epithelial Differentiation [Agilent-014850 array data] Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-10-09 | E-GEOD-24981 | biostudies-arrayexpress
TranscriptomicsExpression data from siRNA knockdown of Ehf in primary human corneal epithelial cells
Ehf is a transcriptional regulator that is highly expressed and enriched in corneal epithelium. To gain insights into the role of Ehf in the corneal epithelium, we performed siRNA knockdown of Ehf in primary human corneal epithelial cells. Primary human corneal epithelial cells were transfected with...
ORGANISM(S): Homo sapiens 
2013-01-01 | E-GEOD-43157 | biostudies-arrayexpress
ProteomicsHuman corneal epithelial cells internalize Aspergillus flavus spores by actin mediated endocytosis
Mycotic leratitis is the corneal inflammation predominantly caused by Fusarium and Aspergillus species. Corneal epithelium is the earliest cell type encounter the invading pathogen. The innate immune responses of human corneal epithelial cells against Aspergillus flavus is not known. Here we studied...
ORGANISM(S): Homo sapiens (Human) 
2021-04-07 | PXD019512 | Pride
Corneal epithelium Actin ring Asperillus flavus Phagosome 
TranscriptomicsCorneal Gene Expression Analysis
Transplantation of amniotic membrane-expanded limbal epithelium (AMLE) in place of donor tissue grafts results in significantly improved outcomes for patients suffering from severe limbal stem cell deficiency; however the reasons for such superior results are unclear. The purpose of this study was t...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-56421 | biostudies-arrayexpress
Sort   by:  
 Page size