Human induced pluripotent stem cells

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Organisms

Homo sapiens (2365)
Mus musculus (110)
Sus scrofa (19)
Rattus norvegicus (11)
Callithrix jacchus (9)
Macaca fascicularis (5)
Danio rerio (4)
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Technology Type

Mass Spectrometry (219)
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Illumina HiSeq 2000 (13)
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Mass spectrometry assay (5)
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ILLUMINA, Illumina HiSeq 2500, Illumina HiSeq 2500 (ILLUMINA) (2)
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Illumina MiSeq, Illumina HiSeq 2000 (2)
Mass spectrometry (2)
SWATH-MS (2)
NMR spectroscopy (2)
HiSeq X Five, ILLUMINA (1)
ILLUMINA, Illumina MiSeq, Illumina HiSeq 2000 (1)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina, unknown (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, Illumina HiSeq 2500 (ILLUMINA), ILLUMINA, Illumina HiSeq 2500 (1)
ILLUMINA, Illumina HiSeq 2000, Illumina HiSeq 2500 (ILLUMINA) (1)
Illumina HiSeq 2500 (ILLUMINA), Illumina HiSeq 2000, Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
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ILLUMINA, Illumina HiSeq 2500 (ILLUMINA), Illumina HiSeq 2000 (1)
Fluorescence intensity (1)
PCR (1)

Instrument Platform

Illumina NovaSeq 6000 (95)
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NA (3)
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Chromium X instrument (10x Genomics); GEM-X FX Chips (10x Genomics); Agilent TapeStation D1000; qPCR (library quantification kit for Illumina platforms) (1)
Chromium X instrument (10x Genomics); GEM-X Flex Sample Preparation v2 Kit (10x Genomics; 1000781); Human Gene Expression Probe Set v1.0.1 (10x Genomics) (1)
Countess 3 FL Automated Cell Counter (Thermo Fisher Scientific; AMQAF2000); GEM-X Flex Sample Preparation v2 Kit (10x Genomics; 1000781) (1)
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Publication Date

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2014 (248)
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2015 (223)
2016 (201)
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2011 (168)
2018 (134)
2019 (126)
2017 (124)
2010 (116)
2009 (46)
2008 (27)
2007 (5)
2005 (1)

UNIPROT ID/AC

A0A024RC46 (19)
A5A3E0 (19)
B4DRV9 (19)
B4DY08 (19)
B4E3A4 (19)
E7EVA0 (19)
H7BY16 (19)
I3L4N8 (19)
O60812 (19)
O75475 (19)
O75475-2 (19)
O75475-3 (19)
O75643 (19)
O76021 (19)
P04406 (19)
P05455 (19)
P06748 (19)
P06748-2 (19)
P06748-3 (19)
P07814 (19)
P07900 (19)
P07910 (19)
P07910-3 (19)
P08238 (19)
P09651 (19)
P09651-2 (19)
P0CG38 (19)
P0CG39 (19)
P12956 (19)
P13639 (19)

ENSEMBL ID

ENSG00000247315 (11)
ENSG00000170477 (7)
ENSG00000204131 (2)
ENSG00000147251 (1)

CHEBI ID

CHEBI:15428 (4)
CHEBI:17115 (4)
CHEBI:16467 (4)
CHEBI:18019 (4)
CHEBI:17203 (4)
CHEBI:15891 (4)
CHEBI:16857 (4)
CHEBI:15354 (4)
CHEBI:17895 (4)
CHEBI:17295 (4)
CHEBI:17287 (3)
CHEBI:16856 (3)
CHEBI:16811 (3)
CHEBI:30794 (3)
CHEBI:15741 (3)
CHEBI:17053 (3)
CHEBI:16015 (3)
CHEBI:32816 (3)
CHEBI:16919 (3)
CHEBI:16414 (3)
CHEBI:17191 (3)
CHEBI:16643 (3)
CHEBI:168656 (2)
CHEBI:101085 (2)
CHEBI:185179 (2)
CHEBI:25371 (2)
CHEBI:185337 (2)
CHEBI:185308 (2)
CHEBI:59477 (2)
CHEBI:27772 (2)

Metabolite Name

Glycine (3)
Taurine (3)
Alanine (3)
Glutamine (3)
Aminoadipic acid (2)
PE 42:4 (2)
PC 44:6 (2)
PC 30:3 (2)
PC 42:5 (2)
PC 42:4 (2)
PC 28:1 (2)
PE 36:4 (2)
PE 42:8 (2)
PE 42:7 (2)
PE 42:5 (2)
PE 40:9 (2)
PE 40:8 (2)
PE 40:6 (2)
PE 40:4 (2)
PE 38:7 (2)
PE 38:6 (2)
PE 38:5 (2)
PE 38:3 (2)
PE 36:6 (2)
PE 36:5 (2)
PE 34:4 (2)
PE 32:1 (2)
PE 30:1 (2)
PC 42:9 (2)
PC 42:8 (2)

First Public Date

2025 (412)
2024 (344)
2014 (331)
2026 (328)
2023 (305)
2022 (241)
2021 (230)
2020 (192)
2018 (132)
2019 (123)
2017 (119)
2015 (86)
2016 (72)
2013 (42)
2011 (2)
2012 (1)
2010 (1)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil (4)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (4)
University of Manchester (4)
Department of Clinical Science, University of Bergen, Norway (3)
The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 USA (3)
Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet SE 17177 Stockholm, Sweden. Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119146, Russia. (2)
College of Life Sciences, University of Dundee (2)
DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (2)
Hannover Medical School Institute for Clinical Biochemistry (OE 4340) Carl-Neuberg-Strasse 1 Building J03, Level 04, Room 1291 (Office), Room 1250 (Lab) 30625 Hannover (2)
King’s British Heart Foundation Centre of Research Excellence, King's College London, United Kingdom (2)
Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil. (2)
Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany (2)
Professor of Molecular Biology. Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee ,Dundee, DD1 5EH, Scotland, UK (2)
Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, D-13092 Berlin, Germany Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany (2)
School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland (2)
The University of Melbourne (2)
1 Department of Genetics, Harvard Medical School, Boston, MA 02115 (1)
1. Ludwig Boltzmann Institute for Traumatology The research center in cooperation with AUVA, Donaueschingenstrasse 13, 1200 Vienna, Austria 2. Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, 1200 Vienna, Austria (1)
1Human Embryonic and Induced Pluripotent Stem Cell Unit, Hellenic Pasteur Institute, Athens, Greece 2Laboratory of Cellular and Molecular Neurobiology-Stem Cells, Hellenic Pasteur Institute, Athens, Greece (1)
1Institute of Lung Health and Immunity, Comprehensive Pneumology Center Munich with the CPC-M bioArchive, Helmholtz Center Munich, Research Center for Environmental Health, Member of the German Center of Lung Research (DZL), Germany (1)
Analytical Chemistry Lab Fondazione Istituto Italiano di Tecnologia Via Morego 30, 16163 Genova Italy (1)
Animal Cell Technology Unit, iBET - Instituto de Biologia Experimental e Tecnológica (1)
Assistant Professor of Neurology and Angela Dobson and Lyndon Welch Professor of Neurology Department of Neurology | University of Michigan Health System 109 Zina Pitcher Place, 5015 BSRB | Ann Arbor, MI | 48109 (1)
Assistant Professor of Neurosurgery Department of Neurosurgery Houston Methodist Research Institute Weill Cornell Medical College (1)
Baker Heart & Diabetes Inst. (1)
Baker Heart and Diabetes Institute (1)
Bioanalytical Mass Spectrometry Group,Max-Planck-Institute for Multidisciplinary Sciences,Goettingen, Germany (1)
Bioanalytical Mass Spectrometry, Max Planck Institute for Molecular Biomedicine, Röntgenstr. 20, 48149 Münster, Germany (1)
Biomedical Research Institute, Foundation for Research and Technology-Hellas, University Campus, 45110 Ioannina, Greece (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, The Netherlands; Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht (1)

IsPrivate

False (1)

Model Flag

Non Kinetic (1)

Classification

bacteria (1)

Modification

6-dioxaoctanediamine derivatized cysteine (1)
N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (601)
RNA-seq of coding RNA (237)
RNA-seq of coding RNA from single cells (74)
ChIP-seq (69)
Methylation profiling by array (58)
Comparative genomic hybridization by array (38)
Methylation profiling by high throughput sequencing (23)
Cell line - High-throughput sequencing (17)
Genotyping by array (16)
ATAC-seq (10)
RNA-seq of total RNA (9)
RNA-seq of non coding RNA (9)
Other (7)
Cell line - Single-cell sequencing (5)
Transcription profiling by RT-PCR (5)
DNA-seq (5)
Baseline (4)
ChIP-chip by tiling array (3)
Human - High-throughput sequencing (3)
Cell line - One-color microarray (3)
ChIP-chip by array (3)
Hi-C (3)
Unknown experiment type (2)
Differential (2)
MicroRNA profiling by high throughput sequencing (2)
RIP-seq (2)
ScATAC-seq (2)
Genotyping by high throughput sequencing (2)
Null (1)
Transcription profiling by SAGE (1)

Release Date

2022 (837)
2021 (798)
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2024 (685)
2020 (629)
2019 (533)
2018 (500)
2016 (447)
2017 (447)
2015 (429)
2014 (429)
2013 (299)
2012 (232)
2011 (205)
2026 (140)
2010 (140)
2009 (56)
2008 (26)
2007 (3)
2006 (1)
2005 (1)
2001 (1)

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1H NMR metabolite monitoring during the differentiation of human induced pluripotent stem cells provides new insights into the molecular events that regulate embryonic chondrogenesis

The integration of cell metabolism with signalling pathways, transcription factor networks and epigenetic mediators is critical in coordinating molecular and cellular events during embryogenesis. Induced pluripotent stem cells (IPSCs) are an established model for embryogenesis, germ layer specificat...

2023-05-24 | MTBLS4854 | MetaboLights

Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs with high efficiency in chemically defined and xeno-free conditions. Despi...

2018-04-24 | MTBLS425 | MetaboLights

Endogenous THBS1 is C-mannosylated by human induced pluripotent stem cells.

We used a human thrombospondin-1 (THBS1) fragment comprising thrombospondin type 1 repeats (TSRs) 1 to 3, which was recombinantly expressed in HEK 293T cells and digested with AspN to determine chromatographic retention times and to optimise MS parameters. We detected two peptides from TSR2 and TSR3...

ORGANISM(S): Homo Sapiens

2021-05-12 | PXD024117 | panorama

Quantitative proteomics for efficient differentiation of human induced pluripotent stem cells into neural stem cells using data independent acquisition mass spectrometry.

Human induced pluripotent stem cells were differentiated into NSC for 7 days. Cells on days 0, 1, 2, 3, 5 and 7 of differentiation (2.0 × 10⁶) were washed twice with DPBS (−) and then mixed with 100 μL of dissolution buffer consisting of 12 mM sodium deoxycholate, 12 mM N-lauroylsarcosine, 100 mM Tr...

ORGANISM(S): Homo Sapiens (human)

2022-06-27 | PXD034925 | JPOST Repository

Transcription profiling of human induced pluripotent stem cells signature and memory retention

Transient expression of two factors, or from Oct4 alone, resulted in efficient generation of human iPSCs. The reprogramming strategy described revealed a potential transcriptional signature for human iPSCs yet retaining the gene expression of donor cells in human reprogrammed cells free of viral and...

ORGANISM(S): Homo sapiens

2009-12-19 | E-GEOD-18618 | biostudies-arrayexpress

Transcription profiling by array of human hepatic cells derived from foreskin fibroblast cell line and from embryonic stem cells.

Reprogrammed somatic cells offer a valuable source of pluripotent cells that have the potential to differentiate into many cells types and provide a new tool for regenerative medicine. In the present study we differentiated induced pluripotent stem cells (iPS cells) into hepatic cells. We first show...

ORGANISM(S): Homo sapiens

2009-08-07 | E-GEOD-14897 | biostudies-arrayexpress

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

This SuperSeries is composed of the following subset Series: GSE23402: Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells (Affymetrix) GSE23455: Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells ...

ORGANISM(S): Homo sapiens

2010-08-08 | E-GEOD-22499 | biostudies-arrayexpress

Human iPS cell proteome

Rapid and deep profiling of human induced pluripotent stem cell proteome analysis by one-shot nano LC-MS/MS with meter-scale monolithic silica capillary columns.

ORGANISM(S): Homo Sapiens (human)

2016-06-20 | PXD004528 | JPOST Repository

Large intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, CD34+ cells, and CD34+ derived induced pluripotent stem cells (LincRNA expression)

LincRNA expression profiles of human embryonic stem cells, CD34+ cells, and CD34+ derived induced pluripotent stem cells Total RNA was extracted from human ESCs, CD34+ cells, and CD34+ derived iPSC lines, then hybridized to Nimblegen tiling array GPL8792; Human lincRNA 391k Tiling Array V2

ORGANISM(S): Homo sapiens

2010-11-10 | E-GEOD-23970 | biostudies-arrayexpress

Large intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, fibroblasts, and fibroblast-derived induced pluripotent stem cells (LincRNA expression)

Expression profiling of non coding RNAs using tilling arrays from ES, Fibroblasts and Fibroblasts derived iPSC LincRNA profiles of human embryonic stem cells, fibroblasts, and fibroblast-derived induced pluripotent stem cells Total RNA was extracted from human ESCs, fibroblast, and fibroblast-derive...

ORGANISM(S): Homo sapiens

2010-11-10 | E-GEOD-24181 | biostudies-arrayexpress

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