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TranscriptomicsRNA-sequencing of human induced pluripotent stem cell-derived intestinal epithelial organoids
The purpose of this study was to characterise iPSC-derived human intestinal epithelial organoids (iPSCo) by comparing these cultures with primary purified intestinal epithelial cells (IEC). Intestinal epithelial organoid (IEO) cultures were derived from at least three different lines of iPSCs, RNA ...
ORGANISM(S): Homo sapiens 
2018-10-22 | E-MTAB-7306 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling of intestinal epithelial cells from paediatric biopsies including Inflammatory Bowel disease and healthy controls
We purified the intestinal epithelial cells from biopsies taken from the ileum and colon of a paediatric cohort of IBD patients and healthy controls
ORGANISM(S): Homo sapiens 
2017-10-20 | E-MTAB-5463 | biostudies-arrayexpress
TranscriptomicsDNA-methylation profiling of human induced pluripotent stem cell -derived intestinal epithelial organoids
The purpose of this study was to characterise iPSC-derived human intestinal epithelial organoids (iPSCo) by comparing these cultures with primary purified intestinal epithelial cells (IEC). Intestinal epithelial organoid (IEO) cultures were derived from at least three different lines of iPSCs, DNA ...
ORGANISM(S): Homo sapiens 
2018-10-23 | E-MTAB-7289 | biostudies-arrayexpress
MetabolomicsLipidomic analysis of Toxoplasma gondii extracellular vesicles across host cell types

Introduction. Toxoplasma gondii is an obligate intracellular parasite with an exceptional capacity to colonize a broad range of host species and cell types. Successful infection depends on its ability to manipulate host metabolism, including lipid pathways that are essential for membrane biogenes...

2026-02-11 | MTBLS13253 | MetaboLights
GenomicsNext Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment
Next Generation Sequencing of normal human intestinal epithelial cell lines, CRC cell lines and CRC cell lines with hypoxia treatment
PRJNA687875 | ENA
Transcriptomics21T series cell lines show distinct stage-specific gene expression alterations
Pathologic and epidemiologic evidence has led to a histologic model of breast cancer progression that involves advancement through specific morphologic stages including atypical ductal hyperplasia (ADH), ductal carcinoma in situ (DCIS) and invasive mammary carcinoma (IMC), although not necessarily a...
ORGANISM(S): Homo sapiens 
2010-04-06 | E-GEOD-18370 | biostudies-arrayexpress
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
TranscriptomicsHuman epithelial cell response to bacterial signal indole
Indole is a bacterial signal secreted by pathogenic and commensal Escherichia coli in the stationary phase at high concentrations (~600 µM). Prior work from our lab has shown that indole decreases E. coli O157:H7 (EHEC) chemotaxis, motility, attachment to epithelial cells and biofilm formation. How...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-14379 | biostudies-arrayexpress
TranscriptomicsAdhesion and bacteriocin production by Lactobacillus salivarius influence the intestinal epithelial cell transcriptional response
The effect of epithelial cell-bacterial interaction on gene transcription in the epithelial cells and bacterial cells in vitro. The transcriptional response elicited by the UCC118 sortase deletion mutant will be compared to that of the wild type UCC118.
ORGANISM(S): Homo sapiens 
2012-07-27 | E-MEXP-3616 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human intestinal organoids infected with Salmonella enterica at 2.5h and 8h post infection
The purpose of this experiment was to identify intestinal epithelial responses to various strains of Salmonella enterica. Human intestinal organoids were infected with three serovars of Salmonella; Typhimurium, Enteritidis and Typhi, as well as type 3 secretion system -1 and -2 mutants in Typhimuriu...
ORGANISM(S): Homo sapiens 
2021-10-01 | E-MTAB-10451 | biostudies-arrayexpress
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