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MetabolomicsResveratrol metabolism in HepG2 (human hepatocytes), HaCaT (human keratinocytes), and C2C12 (mouse myoblasts)
Resveratrol (RESV) is a plant polyphenol, which is thought to have beneficial metabolic effects in laboratory animals as well as in humans. Following oral administration, RESV is immediately catabolized, resulting in low bioavailability. This study compared RESV metabolites and their tissue distribu...
MTBLS127 | MetaboLights
MetabolomicsHuman oral keratinocytes growth and proliferation based on culture medium volume
Not available
ORGANISM(S): Homo sapiens 
ST000690 | MetabolomicsWorkbench
MetabolomicsMetabolic analysis of primary HPV18-genome containing human foreskin keratinocytes compared to untransfected donor-matched controls.
Not available
ORGANISM(S): Homo sapiens 
ST002448 | MetabolomicsWorkbench
TranscriptomicsReal-time quantitative PCR analysis of microRNA in keratinocytes and reconstituted epidermis
Analysis of microRNA expression in keratinocytes by relative quantification (RQ) using the comparative Ct method. Real-time quantitative PCR analysis of microRNA in keratinocytes or reconstituted epidermis exposed to IL-22, LPS or UV radiation or a small molecule drug. Keratinocytes or reconstituted...
ORGANISM(S): Homo sapiens 
2013-05-23 | E-GEOD-41838 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HPV-immortalized keratinocytes
To identify early processes in carcinogenesis, we used an in vitro model, based on the initiating event in cervical cancer, human papillomavirus (HPV) transformation of keratinocytes. We compared gene expression in primary keratinocytes (K) and HPV16-transformed keratinocytes from early (E) and late...
ORGANISM(S): Homo sapiens 
2009-05-02 | E-GEOD-15156 | biostudies-arrayexpress
TranscriptomicsPhevalin (aureusimine B) production by Staphylococcus aureus biofilm and impacts on human keratinocyte gene expression
Staphylococcus aureus produces the cyclic dipeptides tyrvalin and phevalin (aureusimine A and B, respectively). A previous study reported that S. aureus mutants not capable of producing these compounds were less virulent in vivo through the deranged regulation of virulence factor genes. These findin...
ORGANISM(S): Homo sapiens 
2012-10-01 | E-GEOD-32920 | biostudies-arrayexpress
ProteomicsAnti-Ferroptotic Effect of Cannabidiol in Human Skin Keratinocytes Characterized by Data-Independent Acquisition-Based Proteomics
SWATH-MS data for human keratinocytes (HaCaT cell line), sample 010-012 indicates HaCaT cells with no treatment, sample 013-015 indicates HaCaT cells induced by erastin, sample 0016-018 indicates HaCaT cells treated by erastin and CBD. For more detailed information, please contact Dr.Chang Liu (hich...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-03-18 | MSV000094348 | MassIVE
TranscriptomicsTranscription profiling time series of human epidermal keratinocytes treated with Oncostatin-M
Cultured epidermal keratinocytes treated with OsM 1, 4, 24 & 48hrs, and Skinethic epidermal substitutes treated 1, 4, 24, 48h & 7days, each with untreated control Experiment Overall Design: Each timepoint has treated/untreated matched control. Experiment Overall Design: Skinethic 4h treated was repl...
ORGANISM(S): Homo sapiens 
2007-12-12 | E-GEOD-2822 | biostudies-arrayexpress
TranscriptomicsHuman keratinocytes have a response to injury that upregulates CCL20 and other genes linking innate and adaptive immunity
In the early stages of wound healing, keratinocytes become “activated” and release inflammatory molecules such as interleukin-1 and interleukin-8 that are linked to innate immune responses and neutrophil recruitment. It is unclear, however, whether keratinocytes release molecules linked to adaptive ...
ORGANISM(S): Homo sapiens 
2011-09-19 | E-GEOD-30355 | biostudies-arrayexpress
TranscriptomicsRNA-seq of IL-4 stimulated human keratinocytes
In this study we aim to determine the role of IL-4/STAT6 in gene expression in human keratinocytes using RNA-sequencing approach. Human keratinocytes were cultured for 2 or 5 days with calcium chloride to induce terminal differentiation as determined by the expression of epidermal differentiation co...
ORGANISM(S): Homo sapiens 
2015-12-15 | E-GEOD-59275 | biostudies-arrayexpress
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