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TranscriptomicsCharacterisation of an oesophageal adenocarcinoma cell line (The MFD-1)
A cell line (MFD-1) was derived from a 55-year old male with oesophageal adenocarcinoma. Using different sources of genetic material from normal and tumour tissue surgically resected, peripheral blood and the derived cell line a high concordance of genotypes calls across the whole genome confirms MF...
ORGANISM(S): Homo sapiens 
2016-10-03 | E-MTAB-4590 | biostudies-arrayexpress
GenomicsAuthentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
Whole genome sequencing (WGS) from snap-frozen oesophageal tumour tissue and germline nucleic acids isolated from peripheral blood mononuclear cells (PBMC) was performed as part of the International Cancer Genome Consortium project and OCCAMS consortium (1,2). Filtered read sequences were mapped to ...
ORGANISM(S): Homo sapiens 
2016-09-09 | E-MTAB-4600 | biostudies-arrayexpress
ProteomicsOesophageal adenocarcinoma global proteomes
We present data of global proteomes for oesophageal adenocarcinoma and for normal adjacent tissue from seven donors.
ORGANISM(S): Homo sapiens (Human) 
2024-12-17 | PXD054428 | Pride
Human oesophageal adenocarcinoma 
TranscriptomicsATAC-seq of oesophageal adenocarcinoma patient samples
Open chromatin profiling (ATAC-seq) of human oesophageal adenocarcinoma patient samples.
ORGANISM(S): Homo sapiens 
2020-09-30 | E-MTAB-8447 | biostudies-arrayexpress
ProteomicsQuantitative Shotgun Proteomics Unveils Candidate Novel Oesophageal Adenocarcinoma-Specific Proteins
Selective markers are needed for earlier diagnosis, optimal staging and treatment of oesophageal adenocarcinoma. This quantitative shotgun proteomic study used patient-matched fresh frozen tissue samples of OAC, normal oesophagus and normal stomach.
ORGANISM(S): Homo sapiens (Human) 
2017-03-31 | PXD004962 | Pride
Shotgun proteomics Tmt Oesophageal adenocarcinoma 
TranscriptomicsATAC-seq of oesophageal adenocarcinoma cell line MFD-1
The open chromatin of new esophageal adenocarcinoma cell line MFD-1 has been profiled by ATAC-seq.
ORGANISM(S): Homo sapiens 
2018-04-06 | E-MTAB-6720 | biostudies-arrayexpress
ProteomicsIdentification of neoantigens in oesophageal adenocarcinoma
We present data from tissues of seven oesophageal adenocarcinomas of CD4 and CD8 T cell epitopes eluted from the cell surface using mass spectrometry (immunopeptidomics) of presented HLA bound peptides.This dataset forms part of the publication:Nicholas, B., Bailey, A., McCann, K.J., Wood, O., Walke...
ORGANISM(S): Homo sapiens (Human) 
2022-09-27 | PXD031108 | Pride
Human Oesophageal adenocarcinoma Immunopeptidome Hla 
ProteomicsProteomic signatures of radioresistance: Alteration of inflammation, angiogenesis and metabolism-related factors in radioresistant oesophageal adenocarcinomav
The clinical management of locally advanced oesophageal adenocarcinoma (OAC) commonly involves neoadjuvant chemoradiotherapy (CRT), but complete pathological response to CRT only occurs in 20-30% of patients, as radioresistance remains a major clinical challenge. In this study we used an established...
ORGANISM(S): Homo sapiens (Human) 
2022-08-18 | PXD020303 | Pride
Oesophageal adenocarcinoma Oac 
GenomicsATAC-seq of oesophageal adenocarcinoma patient samples
ATAC-seq of oesophageal adenocarcinoma patient samples
PRJEB34929 | ENA
TranscriptomicsGene expression profiling of 60 pre-chemotherapy FFPE endoscopic oesophageal adenocarcinoma biopsies
Oesophageal cancer is the ninth most common cancer in the UK and accounts for 5% of all cancer deaths. The incidence of the disease in men has risen 50% in the last 25 years with the commonest pathological subtype in the West being adenocarcinoma, while in East Asia oesophageal squamous cell carcin...
ORGANISM(S): Homo sapiens 
2018-05-10 | E-MTAB-4666 | biostudies-arrayexpress
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