Human pluripotent stem cell

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Chromium X instrument (10x Genomics); GEM-X FX Chips (10x Genomics); Agilent TapeStation D1000; qPCR (library quantification kit for Illumina platforms) (1)

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UNIPROT ID/AC

A0A024RC46 (19)
A5A3E0 (19)
B4DRV9 (19)
B4DY08 (19)
B4E3A4 (19)
E7EVA0 (19)
H7BY16 (19)
I3L4N8 (19)
O60812 (19)
O75475 (19)
O75475-2 (19)
O75475-3 (19)
O75643 (19)
O76021 (19)
P04406 (19)
P05455 (19)
P06748 (19)
P06748-2 (19)
P06748-3 (19)
P07814 (19)
P07900 (19)
P07910 (19)
P07910-3 (19)
P08238 (19)
P09651 (19)
P09651-2 (19)
P0CG38 (19)
P0CG39 (19)
P12956 (19)
P13639 (19)

ENSEMBL ID

ENSG00000247315 (11)
ENSG00000170477 (7)
ENSG00000204131 (2)
ENSG00000147251 (1)

CHEBI ID

CHEBI:11726 (1)
CHEBI:28403 (1)
CHEBI:1117 (1)
CHEBI:19598 (1)
CHEBI:17385 (1)
CHEBI:1430 (1)
CHEBI:19932 (1)
CHEBI:19600 (1)
CHEBI:1169 (1)
CHEBI:19655 (1)
CHEBI:1687 (1)
CHEBI:42317 (1)
CHEBI:23616 (1)
CHEBI:13960 (1)
CHEBI:23093 (1)
CHEBI:3593 (1)
CHEBI:57884 (1)
CHEBI:23094 (1)
CHEBI:3588 (1)
CHEBI:14734 (1)
CHEBI:25843 (1)
CHEBI:872 (1)
CHEBI:28907 (1)
CHEBI:11417 (1)
CHEBI:19325 (1)
CHEBI:19306 (1)
CHEBI:41885 (1)
CHEBI:19307 (1)
CHEBI:18900 (1)
CHEBI:495 (1)

Metabolite Name

Glycine (3)
Taurine (3)
Alanine (3)
Glutamine (3)
Aminoadipic acid (2)
PE 42:4 (2)
PC 44:6 (2)
PC 30:3 (2)
None (2)
PC 42:5 (2)
PC 42:4 (2)
PC 28:1 (2)
PE 36:4 (2)
PE 42:8 (2)
PE 42:7 (2)
PE 42:5 (2)
PE 40:9 (2)
PE 40:8 (2)
PE 40:6 (2)
PE 40:4 (2)
PE 38:7 (2)
PE 38:6 (2)
PE 38:5 (2)
PE 38:3 (2)
PE 36:6 (2)
PE 36:5 (2)
PE 34:4 (2)
PE 32:1 (2)
PE 30:1 (2)
PC 42:9 (2)

First Public Date

2025 (583)
2024 (531)
2026 (483)
2023 (462)
2022 (398)
2014 (364)
2021 (357)
2020 (316)
2019 (224)
2018 (165)
2017 (161)
2015 (116)
2016 (101)
2013 (54)
2011 (2)
2012 (1)

Modelling Approach

Ordinary differential equation model (1)
Constraint-based model (1)

Lab affiliation

Department of Inflammation and Immunity, Gastroenterology and Hepatology. Cleveland Clinic, Cleveland Ohio, USA (6)
The University of Melbourne (6)
Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, SP, Brazil (4)
Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Denmark (4)
University of Manchester (4)
DZNE Munich, Neuroproteomics, Feodor-Lynen Str. 17, 81377 Munich, Germany (3)
Department of Clinical Science, University of Bergen, Norway (3)
Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, Minnesota 55905 United States (3)
Research Group Leader Bulut-Karslioglu lab Dept. of Genome Regulation Max Planck Institute for Molecular Genetics Ihnestrasse 63-73 14195 Berlin GERMANY (3)
The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287 USA (3)
Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet SE 17177 Stockholm, Sweden. Department of Pharmacological & Technological Chemistry, I.M. Sechenov First Moscow State Medical University, Moscow, 119146, Russia. (2)
College of Life Sciences, University of Dundee (2)
DZNE Munich, Neuroproteomics, Feodor-Lynen-Str. 17, 81377 München, Germany (2)
Department of Biochemistry and Molecular Biology, Protein Research group, University of Southern Denmark, Odense, Denmark (2)
EDyP (2)
Hannover Medical School Institute for Clinical Biochemistry (OE 4340) Carl-Neuberg-Strasse 1 Building J03, Level 04, Room 1291 (Office), Room 1250 (Lab) 30625 Hannover (2)
King’s British Heart Foundation Centre of Research Excellence, King's College London, United Kingdom (2)
Lab of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil. (2)
Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany (2)
Murdoch Children's Research Institute, Melbourne, Australia (2)
Professor of Molecular Biology. Centre for Gene Regulation and Expression, School of Life Sciences, University of Dundee ,Dundee, DD1 5EH, Scotland, UK (2)
Proteome Dynamics, Max Delbrück Center for Molecular Medicine, Robert-Rössle-Str. 10, D-13092 Berlin, Germany Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany (2)
Raymond H. Wittcoff Distinguished Professor and Head Department of Biochemistry and Molecular Biophysics Washington University School of Medicine St. Louis, MO 63110 (2)
School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland (2)
Wellcome Trust Sanger Institute (2)
1 Department of Genetics, Harvard Medical School, Boston, MA 02115 (1)
1. Faculty of Biology, Technion - Israel Institute of Technology, Haifa 320003, Israel 2. Computer Science Department, Technion - Israel Institute of Technology, Haifa 320003, Israel (1)
1. Ludwig Boltzmann Institute for Traumatology The research center in cooperation with AUVA, Donaueschingenstrasse 13, 1200 Vienna, Austria 2. Austrian Cluster for Tissue Regeneration, Donaueschingenstrasse 13, 1200 Vienna, Austria (1)
1. School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China. 2. Centre for Translational Stem Cell Biology, The University of Hong Kong, Hong Kong Special Administrative Region, China. (1)
1Human Embryonic and Induced Pluripotent Stem Cell Unit, Hellenic Pasteur Institute, Athens, Greece 2Laboratory of Cellular and Molecular Neurobiology-Stem Cells, Hellenic Pasteur Institute, Athens, Greece (1)

IsPrivate

False (2)

Model Flag

Non Kinetic (1)

Modification

6-dioxaoctanediamine derivatized cysteine (1)
N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (799)
RNA-seq of coding RNA (320)
RNA-seq of coding RNA from single cells (109)
ChIP-seq (107)
Methylation profiling by array (70)
Comparative genomic hybridization by array (43)
Methylation profiling by high throughput sequencing (39)
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2005 (6)
2006 (2)
2001 (2)
2004 (1)
2003 (1)
2002 (1)
1996 (1)

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Metabolomics Identifies Metabolic Markers of Maturation in Human Pluripotent Stem Cell-Derived Cardiomyocytes

Cardiovascular disease is a leading cause of death worldwide. Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) hold immense clinical potential and recent studies have enabled generation of virtually pure hPSC-CMs with high efficiency in chemically defined and xeno-free conditions. Despi...

2018-04-24 | MTBLS425 | MetaboLights

1H NMR metabolite monitoring during the differentiation of human induced pluripotent stem cells provides new insights into the molecular events that regulate embryonic chondrogenesis

The integration of cell metabolism with signalling pathways, transcription factor networks and epigenetic mediators is critical in coordinating molecular and cellular events during embryogenesis. Induced pluripotent stem cells (IPSCs) are an established model for embryogenesis, germ layer specificat...

2023-05-24 | MTBLS4854 | MetaboLights

Metabolomic Profiling of Human Pluripotent Stem Cell Differentiation into Lung Progenitors

Not available

ORGANISM(S): Homo sapiens

ST002055 | MetabolomicsWorkbench

Stirred suspension bioreactors maintain naïve pluripotency of human pluripotent stem cells (hPSCs)

Not available

ORGANISM(S): Homo sapiens

ST001377 | MetabolomicsWorkbench

scRNA-seq to investigate endoderm differentiation from induced human pluripotent stem cells

Single-cell RNA-seq (scRNA-seq) on nocodazole and DMSO treated cells before and after differentiation into endoderm. hPSC colonies were treated with DMSO or 100ng/ml nocodazole for 16 hours and induced to differentiate into definitive endoderm for three days. Single cells were subsequently collected...

ORGANISM(S): Homo sapiens

2019-02-09 | E-MTAB-7008 | biostudies-arrayexpress

Human oocytes reprogram adult somatic cells to pluripotent stem cells [Illumina]

The stem cell lines were generated according to the principle described in Noggle et al., Nature 2011, Oct 5;478(7367):70-5. doi: 10.1038/nature10397. Title: Human oocytes reprogram somatic cells to a pluripotent state. Abstract: The exchange of the oocyte's genome with the genome of a somatic cel...

ORGANISM(S): Homo sapiens

2014-08-12 | E-GEOD-60360 | biostudies-arrayexpress

Proteome analysis of brainstem organoids from human pluripotent stem cells

Brain organoids derived from human pluripotent stem cells recapitulate the course of human brain development. We applied proteomic analysis to human brainstem organoids which were developed by a novel method.

ORGANISM(S): Homo Sapiens (human)

2020-05-01 | PXD016807 | JPOST Repository

Endogenous THBS1 is C-mannosylated by human induced pluripotent stem cells.

We used a human thrombospondin-1 (THBS1) fragment comprising thrombospondin type 1 repeats (TSRs) 1 to 3, which was recombinantly expressed in HEK 293T cells and digested with AspN to determine chromatographic retention times and to optimise MS parameters. We detected two peptides from TSR2 and TSR3...

ORGANISM(S): Homo Sapiens

2021-05-12 | PXD024117 | panorama

The NIH Human Pluripotent Stem Cell Database (Illumina, methylation)

Methylation profiling was performed on DNA samples matched to the RNA samples included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Nineteen undifferentiated human embryonic stem cell lines and 5 human induced pluripotent stem cells were analyzed. Expanded descriptions of metho...

ORGANISM(S): Homo sapiens

2012-10-31 | E-GEOD-34869 | biostudies-arrayexpress

The NIH Human Pluripotent Stem Cell Database (Illumina, snp)

Genotyping was performed on DNA samples matched to the RNA samples included in the NIH Human Pluripotent Stem Cell Database (Series GSE32923). Seventeen undifferentiated human embryonic stem cell lines and 11 human induced pluripotent stem cells were analyzed. Expanded descriptions of methods used a...

ORGANISM(S): Homo sapiens

2012-10-31 | E-GEOD-35157 | biostudies-arrayexpress

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