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ProteomicsProteomic evaluation of decellularized human umbilical artery
Currently the use of tissue engineered small diameter vascular grafts (d< 6 mm) as substitutes in vascular reconstruction has gained significant attention by the cardiovascular surgeons. Cardiovascular disease (CVD) is among the leading causes of death, worldwide. It is estimated that more than 17 m...
ORGANISM(S): Homo sapiens (Human) 
2020-08-10 | PXD020187 | Pride
Proteomics Cardiovascular disease Cytoskeletal proteins Lc/ms Human umbilical arteries Extracellular matrix proteins Biomechanical analysis Collagen Fibronectin Enzymes Decellularization 
TranscriptomicsGene expression in human umbilical cord vein and artery endothelial cells under physiological chronic normoxia (3% O2, PCN) and standard culture normoxia (21% O2, SCN)
Endothelial cells, and many other types of cells too, physiologically reside in low O2 environments (~ 2-13% O2 or 15-60 mmHg pO2; [PCN]) relevantly to atmospheric O2 (~ 21% or 160 mmHg pO2 at sea level) in vivo. Such PCN is critical for endothelial functions. The majority of our current knowledge ...
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-49958 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human umbilical arteries and veins
This experiment compares veins with arteries using microarrays.
ORGANISM(S): Homo sapiens 
2008-03-10 | E-TABM-368 | biostudies-arrayexpress
TranscriptomicsUNRAVELING A NOVEL TRANSCRIPTION FACTOR CODE INDUCTIVE FOR THE HUMAN ARTERIAL-SPECIFIC ENDOTHELIAL CELL SIGNATURE
Endothelial cells (EC) lining arteries and veins have distinct molecular and functional signatures. The (epi)genetic regulatory mechanisms underlying this heterogeneity in human EC are incompletely understood. Using genome-wide microarray screening we established a specific fingerprint of freshly is...
ORGANISM(S): Homo sapiens 
2014-01-07 | E-GEOD-43475 | biostudies-arrayexpress
UnknownVitrified Human Umbilical Arteries as Potential Grafts for Vascular Tissue Engineering.
Not available
S-EPMC7260347 | biostudies-literature
TranscriptomicsMethylation profiling by EPIC microarray of human umbilical artery smooth muscle cells (HUASMCs) and human aortic smooth muscle cells (HAoSMCs)
Methylation profiling by EPIC microarray was performed on 3 human umbilical artery smooth muscle cells (HUASMCs) and human aortic smooth muscle cells (HAoSMCs) to assess CpG methylation in proximity to cardiovascular disease-associated variants.
ORGANISM(S): Homo sapiens 
2025-12-01 | E-MTAB-15426 | biostudies-arrayexpress
UnknownVasodilation promoted by (E,E)-farnesol involving ion channels in human umbilical arteries.
Not available
S-EPMC10333471 | biostudies-literature
TranscriptomicsTranscription profiling of human macrophage Mono-Mac-6 cell or HUVEC cell one treated with leukotriene
Human umbilical vein endothelial cells (HUVEC) or the human macrophage cell line, Mono-Mac-6, treated with Leukotriene D4 for 1 hour
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-1644 | biostudies-arrayexpress
UnknownUV-B Filter Octylmethoxycinnamate Is a Modulator of the Serotonin and Histamine Receptors in Human Umbilical Arteries.
Not available
S-EPMC9139053 | biostudies-literature
UnknownTwisting the theory on the origin of human umbilical cord coiling featuring monozygotic twins.
Not available
S-EPMC11147950 | biostudies-literature
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