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TranscriptomicsThe Exoribonuclease Nibbler Controls 3' End Processing of MicroRNAs in Drosophila
MicroRNAs (miRNAs) are endogenous noncoding small RNAs with important roles in many biological pathways; their generation and activity are under precise regulation. Emerging evidence suggests that miRNA pathways are precisely modulated with controls at the level of transcription, processing, and sta...
ORGANISM(S): Drosophila melanogaster 
2011-11-17 | E-GEOD-31689 | biostudies-arrayexpress
TranscriptomicsModeling Familial Cancer with iPSC Approaches
In vitro modeling of human disease has recently become feasible with the adoption of induced pluripotent stem cell (iPSC) technology. Here, we established patient-derived iPSCs from an Li-Fraumeni Syndrome (LFS) family and investigated the role of mutant p53 in the development of osteosarcoma (OS). ...
ORGANISM(S): Homo sapiens 
2015-04-10 | E-GEOD-58123 | biostudies-arrayexpress
UnknownIdentification of Cathepsin L as the Molecular Target of Hydroxychloroquine With Chemical Proteomics.
Not available
S-EPMC12719729 | biostudies-literature
TranscriptomicsiCLIP and NGS to map protein-RNA interactions for U1-snRNP proteins in Trypanosoma brucei
Individual-nucleotide resolution UV-crosslinking and immunoprecipitation (iCLIP) combined with high-throughput sequencing was performed to generate genome-wide binding maps of two U1-snRNP proteins: U1C and U1-70K in Trypanosoma brucei. 3 (2) biological replicates of U1C (U1-70K) -specific co-immuno...
ORGANISM(S): Trypanosoma brucei 
2014-05-16 | E-GEOD-43848 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse embryonic stem cell differentiation following treatment with DKK1
Assessed effect of DKK1 treatment on gene expression during the first four days of ES cell differentiation in serum containing medium.
ORGANISM(S): Mus musculus 
2006-12-31 | E-MEXP-759 | biostudies-arrayexpress
UnknownUnlocking Liquid Sulfur Chemistry for Fast-Charging Lithium-Sulfur Batteries.
Not available
S-EPMC10510576 | biostudies-literature
MetabolomicsDifferential role of sphingomyelin in influenza virus, rhinovirus and SARS-CoV-2 infection of Calu-3 cells
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
UnknownProlonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19.
Not available
S-EPMC8529231 | biostudies-literature
UnknownMitochondrial genome assembly of the Chinese endemic species of Camellia luteoflora and revealing its repetitive sequence mediated recombination, codon preferences and MTPTs.
Not available
S-EPMC11971748 | biostudies-literature
UnknownDefining the core essential genome of Pseudomonas aeruginosa.
Not available
S-EPMC6525520 | biostudies-literature
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