The epigenomic landscape of the human genome, in particular DNA methylation, is increasingly recognised as an important driver of phenotypic diversity in health and disease. However, the impact that genetic variation and changes in lifestyle and ecological habitat have on this epigenetic mark remain...
This a model from the article:
One-dimensional rabbit sinoatrial node models: benefits and limitations.
Garny A, Kohl P, Hunter PJ, Boyett MR, Noble D. J Cardiovasc Electrophysiol
2003 Oct;14(10 Suppl):S121-32 14760914
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Ab...
Ischaemic cardiomyopathy (ICM) is the most common cause of heart failure (HF) and often coexists with diabetes mellitus (DM). Yet, their combined effects are seldom investigated and are poorly understood. We performed multi-omic analyses of end-stage ICM with DM (ICM-DM), ICM-No DM, non-ischaemic ca...
