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ProteomicsLC-MS/MS analyses of purified virions of influenza A and B viruses, grown in a range of hosts.
LC-MS/MS analyses of purified virions of influenza A and B viruses, grown in a range of hosts. Described in Hutchinson et al. 'Conserved and host-specific features of influenza virion architecture.'
ORGANISM(S): Bos Taurus (ncbitaxon:9913) Canis Familiaris (canine) Influenza Viruses Gallus Gallus (ncbitaxon:9031) 
2014-06-16 | MSV000078740 | MassIVE
TranscriptomicsResistance of primary ovarian cancer cells to oncolytic adenoviruses part2 of 2
The mechanisms of primary ovarian cancer cells for resistance to viral oncolysis were investigated using Ad5/35.IR.E1A/TRAIL on clonal cultures derived from ovc316m cells. Part 2 of 2, 26 clonal ovc316m cultures additionally to Resistance of primary ovarian cancer cells to oncolytic adenoviruses par...
ORGANISM(S): Homo sapiens 
2009-04-01 | E-GEOD-15351 | biostudies-arrayexpress
TranscriptomicsResistance of primary ovarian cancer cells to oncolytic adenoviruses part1 of 2
The mechanisms of primary ovarian cancer cells for resistance to viral oncolysis were investigated using Ad5/35.IR.E1A/TRAIL on clonal cultures derived from ovc316m cells. Part 1 of 2, initital study involving 5 clonal ovc316m cultures Cells were infected for 8 days and cell survival determined by M...
ORGANISM(S): Homo sapiens 
2010-06-20 | E-GEOD-15350 | biostudies-arrayexpress
ProteomicsAn in vivo screening platform using PDX models reveals KEAP1, USP22 and other drivers of chemoresistance in small cell lung cancer
Small cell lung cancer (SCLC) is characterized by exquisite chemosensitivity followed by rapid emergence of chemoresistance. To identify genetic events that drive resistance to cisplatin-etoposide chemotherapy, we conducted cDNA overexpression and CRISPR knockout screens in an in vivo platform cente...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2026-04-20 | PXD048813 | Pride
Crispr knockout Global phosphoproteome Small cell lung cancer Imac Tmt Pdx 
UnknownCalcium plus vitamin D supplementation and the risk of nonmelanoma and melanoma skin cancer: post hoc analyses of the women's health initiative randomized controlled trial.
Not available
S-EPMC3157967 | biostudies-literature
MetabolomicsHost-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles
Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...
2018-02-12 | MTBLS452 | MetaboLights
TranscriptomicsThe effect of progerin expression on alternative splicing in keratinocytes of HGPS mice
Exon level expression analysis for the HGPS pathological aging study data set to analyze the effect of progerin expression on alternative splicing in keratinocytes of HGPS mice. Analysis of the effect of pathological aging (transgenic progerin expression) on alternative splicing (AS) using exon mic...
ORGANISM(S): Mus musculus 
2015-11-01 | E-GEOD-67288 | biostudies-arrayexpress
TranscriptomicsGenome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function [cultured cortical neurons]
To examine potential differences in activity-dependent gene expression, we analyzed mRNA expression in cultured neurons isolated from Wild-type vs MeCP2 S421A mice at 0 (unstimulated), 1 or 6 hours after membrane depolarization by exposure to high extracellular KCl (55mM) All mice were male litterma...
ORGANISM(S): Mus musculus 
2011-09-07 | E-GEOD-31849 | biostudies-arrayexpress
TranscriptomicsSelective inhibition of Homo sapiens M1 macrophages where SP140 mRNA is inhibited using siRNA
As part of our study in understanding the role of SP140 in inflammatory pathways in macrophages, we inhibited SP140 mRNA using siRNA. Peripheral blood mononuclear cells (PBMCs) were obtained from whole blood of healthy donors (from Sanquin Institute Amsterdam or from GSK Stevenage Blood Donation U...
ORGANISM(S): Homo sapiens 
2022-07-22 | E-MTAB-12011 | biostudies-arrayexpress
UnknownCombinatorial control of temporal gene expression in the Drosophila wing by enhancers and core promoters.
Not available
S-EPMC3641971 | biostudies-literature
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