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TranscriptomicsHydrogen sulfide stimulates Mycobacterium tuberculosis respiration and growth to exacerbate TB disease
The aim of this experiment was to determine how exposure of Hydrogen sulfide impacts gene expression in Mycobacterium tuberculosis. RNA was isolated from actively growing mycobacterial cells (0.6-0.8 OD600) using Trizol according to established protocols (27). Briefly, cells were exposed to 25 µM G...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2020-01-04 | E-MTAB-7421 | biostudies-arrayexpress
TranscriptomicsHydrogen sulfide (H2S) modulates lifespan of C.elegans
Hydrogen sulfide (H2S) is formed naturally from L-cysteine in a variety of mammalian and non-mammalian cells. To date, numerous biological effects have been ascribed to H2S including control of cardiovascular, immune and nervous function. Over or under production of H2S has been observed in several ...
ORGANISM(S): Caenorhabditis elegans 
2013-07-30 | E-GEOD-16975 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse CD4+ T cells
Hydrogen sulfide (H2S) is an endogenous gasotransmitter and is capable of regulating various endogenous signaling pathways, inculding inflamation and immune response. In mammals, H2S is mainly generated by two pyridoxal-5’-phosphate-dependent enzymes, termed cystathionine beta-synthase (CBS) and cys...
ORGANISM(S): Mus musculus 
2015-07-22 | E-GEOD-59241 | biostudies-arrayexpress
TranscriptomicsHydrogen sulfide regulation of the DNA methylation profile of rice plants under drought stress
To investigate the effect of H2S on DNA methylation of plants submitted to drought stress, we performed transcriptome sequencing analysis in four experimental treatments: rice watered plants (control sample, C), rice plants watered with NaHS solution, as sulfide donor (sulfide treatment, S), rice pl...
ORGANISM(S): Oryza sativa Japonica Group 
2026-07-01 | E-MTAB-15231 | biostudies-arrayexpress
TranscriptomicsGlobal gene profiling comparison between hydrogen sulfide- and N-methyl-D-aspartate-induced neuronal deaths
Hydrogen sulfide (H2S), present in abundance in the mammalian brain, has recently been demonstrated to induce a dose- and time-dependent apoptotic-necrotic continuum in murine primary cortical neurons, which was successfully attenuated upon application of N-methyl-D-aspartate (NMDA) receptor antagon...
ORGANISM(S): Mus musculus 
2013-01-23 | E-GEOD-16035 | biostudies-arrayexpress
TranscriptomicsHydrogen sulfide regulation of the transcriptional profile of rice plants under drought stress
To investigate the effect of H2S on the rice transcriptomic responses to drought stress, we performed transcriptome sequencing analysis in four experimental treatments: rice watered plants (control sample, C), rice plants watered with NaHS solution, as sulfide donor (sulfide treatment, S), rice plan...
ORGANISM(S): Oryza sativa Japonica Group 
2026-07-01 | E-MTAB-15224 | biostudies-arrayexpress
ProteomicsProteomics Analysis of the Inferior Colliculus following Acute Hydrogen Sulfide
We used broad-spectrum proteomics to search for key molecules in H2S induced neurotoxicity. Mice were subjected to acute whole body exposure up to 750ppm of H2S at day1 for 40min, followed by 15min daily exposure. Following H2S exposure, inferior colliculi were harvested on day1, day2, and day4 and...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2017-10-26 | MSV000081650 | MassIVE
TranscriptomicsThe Global Transcriptional Response of Fission Yeast to Hydrogen Sulfide
Hydrogen sulfide (H2S) as an important gasotransmitter has fundamental roles in human diseases. The cellular effect of H2S has received lots of attention recently. H2S can affect ion channels, transcription factors and kinase in mammals. The mechanism of cellular effect of H2S is not completely unde...
ORGANISM(S): Schizosaccharomyces pombe 
2012-06-14 | E-GEOD-30025 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat nasal respiratory epithelium laser capture microdissected after exposure to hydrogen sulfide
Hydrogen sulfide (H2S) is a naturally occurring gas that is also associated with several industries. The potential for widespread human inhalation exposure to this toxic gas is recognized as a public health concern. The nasal epithelium is particularly susceptible to H2S-induced pathology. Injury...
ORGANISM(S): Rattus rattus 
2009-10-18 | E-GEOD-5349 | biostudies-arrayexpress
ProteomicsSEVERE CONSEQUENCES OF A HIGH-LIPID DIET INCLUDE HYDROGEN SULFIDE DYSFUNCTION AND DISEASE AGGRESSION IN GLIOBLASTOMA
Glioblastoma (GBM) remains among the deadliest of human malignancies, and the emergence of the cancer stem cell (CSC) phenotype represents a major challenge to durable treatment response. Because the environmental and lifestyle factors that impact CSC populations are not clear, we sought to understa...
ORGANISM(S): Homo sapiens (Human) 
2021-05-25 | PXD023685 | Pride
Metabolism Glioblastoma Diet Cancer stem cells Hydrogen sulfide 
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