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ProteomicsDual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia
The architecture of chromatin specifies eukaryotic cell identity by controlling transcription factor access to sites of gene regulation. Here we describe a dual transposase/peroxidase approach, integrative DNA And Protein Tagging (iDAPT), which detects both DNA (iDAPT-seq) and protein (iDAPT-MS) ass...
ORGANISM(S): Homo sapiens (Human) 
2020-11-02 | PXD022252 | Pride
Human Tmt Idapt Hematopoietic cancer cells 
GenomicsDual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (CUT&RUN)
The architecture of chromatin specifies eukaryotic cell identity by controlling transcription factor access to sites of gene regulation. Here we describe a dual transposase/peroxidase approach, integrative DNA And Protein Tagging (iDAPT), which detects both DNA (iDAPT-seq) and protein (iDAPT-MS) ass...
ORGANISM(S): Homo sapiens 
2020-11-01 | GSE158348 | GEO
GenomicsDual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (ATAC-Seq)
The architecture of chromatin specifies eukaryotic cell identity by controlling transcription factor access to sites of gene regulation. Here we describe a dual transposase/peroxidase approach, integrative DNA And Protein Tagging (iDAPT), which detects both DNA (iDAPT-seq) and protein (iDAPT-MS) ass...
ORGANISM(S): Homo sapiens 
2020-11-01 | GSE158346 | GEO
UnknownDual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia.
Not available
S-EPMC8272231 | biostudies-literature
UnknownMonitoring the Implementation of Tobacco Cessation Support Tools: Using Novel Electronic Health Record Activity Metrics.
Not available
S-EPMC10020903 | biostudies-literature
ProteomicsSARS-CoV-2 spike sequence dictates host TP53 activity and COVID-19 pathogenicity
SARS-CoV-2 induces widespread transcriptomic changes in host cells upon infection, in part through activation and modulation of innate immunity pathways and downstream gene regulation. However, the mechanisms by which SARS-CoV-2 and its evolutionary variants differentially affect host cell transcrip...
ORGANISM(S): Chlorocebus sabaeus 
2023-09-09 | PXD034648 | Pride
Idapt-ms Sars-cov-2 Covid-19 Tp53 Spike 
GenomicsDual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (ATAC-Seq)
Dual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (ATAC-Seq)
PRJNA664953 | ENA
GenomicsDual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (CUT&RUN)
Dual DNA/protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia (CUT&RUN)
PRJNA664954 | ENA
TranscriptomicsDifferences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53 [RNA-Seq]
COVID-19 remains a significant public health threat due to the ability of SARS-CoV-2 variants to evade the immune system and cause breakthrough infections. Although pathogenic coronaviruses such as SARS-CoV-2 and MERS-CoV lead to severe respiratory infections, how these viruses affect the chromatin ...
ORGANISM(S): Homo sapiens Chlorocebus sabaeus 
2023-09-30 | GSE241891 | GEO
GenomicsDifferences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53 [miRNA-Seq]
COVID-19 remains a significant public health threat due to the ability of SARS-CoV-2 variants to evade the immune system and cause breakthrough infections. Although pathogenic coronaviruses such as SARS-CoV-2 and MERS-CoV lead to severe respiratory infections, how these viruses affect the chromatin ...
ORGANISM(S): Homo sapiens 
2023-09-30 | GSE241890 | GEO
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