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MetabolomicsChemoresistant Cancer Cell Lines are Characterized by Migratory, Amino Acid Metabolism, Protein Catabolism and IFN1 Signalling Perturbations
Not available
ORGANISM(S): Homo sapiens 
ST002104 | MetabolomicsWorkbench
UnknownMitochondrial morphology and MAVS-IFN1 signaling pathway in muscles of anti-MDA5 dermatomyositis.
Not available
S-EPMC7951095 | biostudies-literature
TranscriptomicsActivation of IFN1 signaling by TAK-981 in blood, spleen, or tumor of A20-tumor bearing or B16F10-tumor bearing mice
Intravenous administration of TAK-981 to Balb/c or C57BL/6 mice bearing A20 or B16F10 syngeneic tumors, respectively, resulted in a strong induction of IFN1 pathway genes in peripheral blood leukocytes, spleen and A20 tumor tissues. TAK- 981 dependent upregulation of IFN1 mRNA signature was determin...
ORGANISM(S): Mus musculus 
2021-04-23 | GSE173114 | GEO
Genomics
Oncorhynchus masou IFN1 gene for type I interferon 1
PRJNA1305699 | ENA
GenomicsActivation of IFN1 signaling by TAK-981 in blood, spleen, or tumor of A20-tumor bearing or B16F10-tumor bearing mice
Activation of IFN1 signaling by TAK-981 in blood, spleen, or tumor of A20-tumor bearing or B16F10-tumor bearing mice
PRJNA723844 | ENA
UnknownThe SUMOylation inhibitor subasumstat potentiates rituximab activity by IFN1-dependent macrophage and NK cell stimulation.
Not available
S-EPMC11022956 | biostudies-literature
UnknownIntrinsic Type 1 Interferon (IFN1) Profile of Uncultured Human Bone Marrow CD45lowCD271+ Multipotential Stromal Cells (BM-MSCs): The Impact of Donor Age, Culture Expansion and IFNα and IFNβ Stimulation.
Not available
S-EPMC7399891 | biostudies-literature
UnknownThe Effects of Clinically Relevant Radionuclides on the Activation of an IFN1 Response Correlate with Radionuclide Half-life and Linear Energy Transfer and Influence Radiopharmaceutical Antitumor Efficacy.
Not available
S-EPMC12316559 | biostudies-literature
ProteomicsSUMO operates from a unique long tandem repeat to keep innate immunity in check
The SUMO pathway mainly functions to repress innate immunity in myeloid cells. Inactivating sumoylation triggers a strong, noncanonical, type I interferon (IFN1) response, amplified and coupled with inflammation upon stimulation. These findings transposed to pre-clinical models with the demonstratio...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-16 | PXD061276 | Pride
Sumo Sumoylation H3.3 Ifn1 H3k9me3 Morc3 
UnknownAmazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis.
Not available
S-EPMC6602282 | biostudies-literature
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