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We have recently isolated IgSF21 (IGIS) as a novel synaptic organizer that selectively promotes inhibitory presynaptic differentiation. To isolate IgSF21 receptor that mediates synapse-promoting activity of IgSF21, we performed proteomics-based screen using cultured hippocampal neurons with IgSF21-c...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-04 | PXD006622 | Pride
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and post-synaptic assembly. How these extracellular interactions translate into intracellular signal transduction for synaptic assembly remain...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-04 | PXD048927 | Pride
Bone autograft healing is a highly orchestrated process that integrates immune activation, vascular ingrowth, and osteogenic remodeling. To define the molecular and cellular programs driving early autograft integration, bulk and single-cell RNA sequencing was used to analyze graft-associated tissues...
ORGANISM(S): Mus musculus 
2026-06-12 | GSE334281 | GEO
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