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UnknownPin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction.
Not available
S-EPMC4197815 | biostudies-literature
UnknownChronic stress induces depression through MDGA1-Neuroligin2 mediated suppression of inhibitory synapses in the lateral habenula.
Not available
S-EPMC11780514 | biostudies-literature
ProteomicsStructural and functional characterization of the IgSF21-Neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization
The prevailing model behind synapse development and specificity is that a multitude of adhesion molecules engage in transsynaptic interactions to induce pre- and post-synaptic assembly. How these extracellular interactions translate into intracellular signal transduction for synaptic assembly remain...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-04 | PXD048927 | Pride
C-jun n-terminal kinase Gabaergic synapse Src kinase Camkii kinase Neurexin2α Signal transduction Igsf21 Neuroligin2 
UnknownAdeno-associated viral overexpression of neuroligin 2 in the mouse hippocampus enhances GABAergic synapses and impairs hippocampal-dependent behaviors.
Not available
S-EPMC6626304 | biostudies-literature
UnknownReversing anxiety by targeting a stress-responsive signaling pathway.
Not available
S-EPMC11295078 | biostudies-literature
UnknownHippocampal neuroligin-2 overexpression leads to reduced aggression and inhibited novelty reactivity in rats.
Not available
S-EPMC3579928 | biostudies-literature
UnknownmicroRNA-218-5p coordinates scaling of excitatory and inhibitory synapses during homeostatic synaptic plasticity.
Not available
S-EPMC12002172 | biostudies-literature
UnknownStructural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.
Not available
S-EPMC10989685 | biostudies-literature
ProteomicsNeuroligin 2 Governs Synaptic Morphology and Function Through RACK1-Cofilin Signaling in Drosophila
Neuroligins are transmembrane cell adhesion proteins well-known for their genetic links to autism spectrum disorders. Neuroligins can function by regulating the actin cytoskeleton, however the factors and mechanisms involved are still largely unknown. Here, using the Drosophila neuromuscular junctio...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-10-06 | PXD045754 | Pride
Lc-ms Drosophila Neuroligin2 
TranscriptomicsmicroRNA-218-5p Coordinates Scaling of Excitatory and Inhibitory Synapses during Homeostatic Synaptic Plasticity
Homeostatic synaptic plasticity (HSP) is a fundamental neuronal mechanism that allows networks to compensate for prolonged changes in activity by adjusting synaptic strength. This process is crucial for maintaining stable brain function and has been implicated in memory consolidation during sleep. W...
ORGANISM(S): Mus musculus 
2025-03-17 | GSE245158 | GEO
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