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TranscriptomicsRNA-seq of splenic follicular B cells from wild-type and IKZF1 L132P mutant mice
Comparing the effect of the L132P variant in ZF1 of IKZF1 on the gene expression in sorted follicular B cells.
ORGANISM(S): Mus musculus 
2021-01-29 | E-MTAB-9975 | biostudies-arrayexpress
TranscriptomicsEfficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia
Alterations of IKZF1, encoding the lymphoid transcription factor IKAROS, are a hallmark of high risk acute lymphoblastic leukemia (ALL), however the role of IKZF1 alterations in ALL pathogenesis is poorly understood. Here we show that in mouse models of BCR-ABL1 leukemia, Ikzf1 and Arf alterations s...
ORGANISM(S): Mus musculus 
2015-09-04 | E-GEOD-68391 | biostudies-arrayexpress
ProteomicsLenalidomide Causes Selective Degradation of IKZF1 and IKZF3 in Multiple Myeloma Cells
Krönke J, Udeshi ND, Narla A, Grauman P, Hurst SN, McConkey M, Svinkina T, Heckl D, Comer E, Li X, Ciarlo C, Hartman E, Munshi N, Schenone M, Schreiber SL, Carr SA, Ebert BL. Science 2014, 343, 301-305. doi:10.1126/science.1244851. Lenalidomide is a drug with clinical efficacy in multiple myeloma an...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-01-26 | MSV000079017 | MassIVE
GenomicsIkzf1 lactylation regulates CD4 T cell differentiation
Ikzf1 lactylation regulates CD4 T cell differentiation
PRJNA941218 | ENA
GenomicsGenome-wide screening of IKZF1 binding in multiple myeloma cells.
Genome-wide screening of IKZF1 binding in multiple myeloma cells.
PRJNA800413 | ENA
GenomicsIKZF1 gene deletions in BCP-ALL promote resistance to cytarabine treatment
IKZF1 gene deletions in BCP-ALL promote resistance to cytarabine treatment
PRJNA982166 | ENA
GenomicsA new pipeline SPICE identifies novel JUN-IKZF1 composite elements
A new pipeline SPICE identifies novel JUN-IKZF1 composite elements
PRJNA957252 | ENA
ProteomicsdCas9 targeted chromatin and histone enrichment for mass spectrometry (Catchet-MS) identifies IKZF1 as a novel target for HIV-1 latency reversal
HIV-1 infected patients virally suppressed by antiviral treatment harbor a persistent reservoir of replication competent latent HIV-1 infected cells, which constitute the main roadblock to a cure. A main strategy for HIV cure aims to stimulate viral gene expression in latently infected cells so that...
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD032975 | Pride
Catchet-ms Ikzf1 Hiv-1 latency reversal 
GenomicscircIkzf1 and Ikzf1 overexpression in Th cells [scRNA-seq A]
circIkzf1 and Ikzf1 overexpression in Th cells [scRNA-seq A]
PRJNA895373 | ENA
GenomicscircIkzf1 and Ikzf1 overexpression in Th cells [scRNA-seq B]
circIkzf1 and Ikzf1 overexpression in Th cells [scRNA-seq B]
PRJNA895375 | ENA
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