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MetabolomicsLuminal metabolome profiles of human microbiota-associated (HMA) mice treated with anti-IL-22 antibody or control antibody
Not available
ORGANISM(S): Mus musculus 
ST001301 | MetabolomicsWorkbench
TranscriptomicsGene expression of Listeria monocytogenes-infected HepG2 hepatocellular carcinoma in the presense of IL-17Aand IL-22
IL-17A and IL-22 induced several inflammation-induced genes and anti-microbial molecules including Pla2g2a and Lcn2 on HepG2 cells when the cells were treated with the cytokines before Listeria monocytogenes infection. HepG2 cells were treated with 50 ng/ml IL-17A and 10 ng/ml IL-22 before L. monocy...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-GEOD-71248 | biostudies-arrayexpress
ModelsKessler2025 - IL-6 and IL-22 pathway in human hepatocytes
IL-6 and IL-22 pathway in human hepatocytes
2025-11-14 | MODEL2509100001 | BioModels
TranscriptomicsRNAseq of small intestinal organoids from mice treated with the cytokines IL-13 and IL-22 for 72 hours in combination with the BMP signaling inhibitor DMH1
The intestinal epithelium is our first line of defense against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we use signatur...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-9185 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of primary human bronchial epithelial cells stimulated with IL-22 and IL-17
Primary HBE cells were stimulated with IL-22 and IL-17, and gene expression was studied using an Affymetrix platform microarray, in order to investigate which genes may be upregulated or downregulated in response to these cytokines. Of particular interest was the host defense genes such as antimicr...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-10240 | biostudies-arrayexpress
TranscriptomicsIL-22 regulation of functional gene expression in salivary gland cells
Microarray analysis using the HumanHT-12 v4 Expression BeadChip was utilized to determine the biological function of IL-22. The data indicate an extensive effect of IL-22 on many major molecular functions including activation of antimicrobial genes and downregulation of immune-associated pathways. ...
ORGANISM(S): Homo sapiens 
2015-10-27 | E-GEOD-74389 | biostudies-arrayexpress
ProteomicsIL-22 Controls Iron-Dependent Nutritional Immunity Against Systemic Bacterial Infections
Host immunity limits iron availability to pathogenic bacteria, but whether immunity limits pathogenic bacteria from accessing host heme, the major source of iron in the body, remains unclear. Using Citrobacter rodentium, a mouse enteric pathogen and Escherichia coli, a major cause of sepsis in hum...
ORGANISM(S): Mus musculus (Mouse) 
2017-02-03 | PXD005666 | Pride
Hemopexin Il-22 Bacterial infection 
TranscriptomicsIdentification of IL-22 regulated genes in the ileum after infection with Toxoplasma gondii
IL-22 acts on epithelial cells and has been shown to induce tissue protective and wound healing responses in these cells. But it has recently been decribed that IL-22 exacerbates ileatis after infection with T. gondii. The goal of the study is to identify the IL-22-dependent genes during T. gondii i...
ORGANISM(S): Mus musculus 
2015-01-31 | E-GEOD-65472 | biostudies-arrayexpress
TranscriptomicsGene expression profile of human epidermal keratinocytes in response to IFNgamma, IL-4, IL-6, IL-17A and IL-22
To understand the role of epidermal keratinocytes in immunopathology of skin diseases with predominant T helper (Th) cell responses, we measured the genome-wide transcriptional profile of human keratinocytes in response to IFNgamma, IL-4, IL-17A or IL-22, major cytokines produced by Th1, Th2, Th17 o...
ORGANISM(S): Homo sapiens 
2014-10-02 | E-GEOD-53751 | biostudies-arrayexpress
TranscriptomicsRNA-seq of small intestinal organoids treated with IL-22 for 0, 1 and 4 hours
The intestinal epithelium is our first line of defence against infections of the gut and the plasticity in cellular differentiation of the intestinal epithelium is an important part of this response. The changes in cellular composition is driven by immune cell derived cytokines. Here we investigate ...
ORGANISM(S): Mus musculus 
2022-05-08 | E-MTAB-11273 | biostudies-arrayexpress
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