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ProteomicsFly RBPome - Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins
Early embryogenesis is characterized by the maternal to zygotic transition (MTZ), in which maternally deposited messenger RNAs are translated and subsequently degraded while zygotic transcription begins. Posttranscriptional gene regulation by RNA-binding proteins (RBPs) is a dominant force controlli...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-04-26 | PXD002992 | Pride
Fly 
ProteomicsRPL12 phosphorylation regulates translation during mitosis - ribo profile B cell -
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The impact of posttranslational modifications has not yet been studied systematically. A...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-31 | PXD009307 | Pride
Ribosome Lc-ms 
ProteomicsRPL12 phosphorylation regulates translation during mitosis - ribo profile HEK293 and HeLa-
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The impact of posttranslational modifications has not yet been studied systematically. A...
ORGANISM(S): Homo sapiens (Human) 
2019-09-09 | PXD009292 | Pride
Ribosome Lc-ms 
ProteomicsRPL12 phosphorylation regulates translation during mitosis - pSILAC B cell -
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The impact of posttranslational modifications has not yet been studied systematically. A...
ORGANISM(S): Homo sapiens (Human) 
2018-08-31 | PXD009276 | Pride
Ribosome Lc-ms 
ProteomicsRPL12 phosphorylation regulates translation during mitosis -ribo profile mESC -
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The impact of posttranslational modifications has not yet been studied systematically. A...
ORGANISM(S): Mus musculus (Mouse) 
2018-08-31 | PXD009268 | Pride
Ribosome Lc-ms 
ProteomicsRPL12 phosphorylation regulates translation during mitosis - pSILAC HEK293 -
Emerging evidence indicates that heterogeneity in ribosome composition can give rise to specialized functions. Until now, research mainly focused on differences in core ribosomal proteins and associated factors. The impact of posttranslational modifications has not yet been studied systematically. A...
ORGANISM(S): Homo sapiens (Human) 
2018-09-03 | PXD009267 | Pride
Ribosome Lc-ms 
ProteomicsIntegrated phosphoproteome and transcriptome analysis reveals Chlamydia-induced epithelial-to-mesenchymal transition in host cells
Chlamydia trachomatis are the etiological agents of a range of diseases and are epidemiologically associated with cervical and ovarian cancers. The interplay between host and chlamydia is highly complex, and to obtain panoramic view of the functional interplay, we performed combinatorial global phos...
ORGANISM(S): Homo sapiens (Human) 
2018-12-07 | PXD011960 | Pride
Chlamydia Phosphoproteomics 
ProteomicsDDX54 regulates transcriptome dynamics during DNA damage response, DDX54 co-IP
The cellular response to genotoxic stress is a well-characterized network of DNA surveillance pathways. The contribution of posttranscriptional gene regulatory networks to the DNA damage response (DDR) has not been extensively studied. Here, we systematically identified RNA-binding proteins differen...
ORGANISM(S): Homo sapiens (Human) 
2018-06-06 | PXD005190 | Pride
Human Co-ip Rbpome Dna damage 
ProteomicsDDX54 regulates transcriptome dynamics during DNA damage response, pSILAC
The cellular response to genotoxic stress is a well-characterized network of DNA surveillance pathways. The contribution of posttranscriptional gene regulatory networks to the DNA damage response (DDR) has not been extensively studied. Here, we systematically identified RNA-binding proteins differen...
ORGANISM(S): Homo sapiens (Human) 
2017-06-12 | PXD006093 | Pride
Human Psilac Dna damage 
ProteomicsDDX54 regulates transcriptome dynamics during DNA damage response, DDX54 BioID
The cellular response to genotoxic stress is a well-characterized network of DNA surveillance pathways. The contribution of posttranscriptional gene regulatory networks to the DNA damage response (DDR) has not been extensively studied. Here, we systematically identified RNA-binding proteins differen...
ORGANISM(S): Homo sapiens (Human) 
2017-06-12 | PXD005191 | Pride
Human Rbpome Dna damage Bioid 
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