Sort   by:  
 Page size 
MetabolomicsBrain-Immune system-Gut Interaction in Chronic Mild Stress (CMS +/- Lacto)
Not available
ORGANISM(S): Mus musculus 
ST000696 | MetabolomicsWorkbench
MetabolomicsMetabolomic changes in Mycobacterium avium subsp. paratuberculosis (MAP) challenged Holstein-Friesian cattle suggest the role of serum amino acids as indicators of immune system activation

INTRODUCTION: Paratuberculosis, commonly known as Johne’s disease, is a chronic intestinal infection of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). Clinical signs, including reduced milk yields, weight loss and diarrhoea, are typically abse...

2022-02-23 | MTBLS2963 | MetaboLights
MetabolomicsImmune Stimulation via Wounding Alters Chemical Profiles of Adult Tribolium castaneum
Group-living individuals experience immense risk of disease transmission and parasite infection. In social and in some non-social insects, disease control with immunomodulation arises not only via individual immune defenses, but also via infochemicals such as contact cues and (defensive) volatiles t...
2023-04-24 | MTBLS2277 | MetaboLights
MetabolomicsKynurenic acid underlies sex-specific immune responses to COVID-19
Sex-related differences in Coronavirus Disease (COVID-19) severity and mortality exist, with the male sex being a potential risk factor1. It was recently shown that patients with mild to moderate SARS-CoV-2 infection have elevated levels of inflammatory cytokines and chemokines, and sex-differences ...
2020-09-08 | MTBLS1987 | MetaboLights
MetabolomicsIntegration of metabolomics, genomics and immune phenotypes reveals the causal roles of metabolites in disease

BACKGROUND: Recent studies highlight the role of metabolites in immune diseases, but it remains unknown how much of this effect is driven by genetic and non-genetic host factors.

RESULT: We systematically investigate circulating metabolites in a cohort of 5...

2021-06-14 | MTBLS2633 | MetaboLights
MetabolomicsCroquemort elicits activation of the immune deficiency pathway in ticks
The immune deficiency (IMD) pathway directs host defense in arthropods upon bacterial infection. In Pancrustacea, peptidoglycan recognition proteins sense microbial moieties and initiate nuclear factor-κB-driven immune responses. Proteins that elicit the IMD pathway in non-insect arthropods remain e...
2023-04-27 | MTBLS686 | MetaboLights
MetabolomicsThe gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
The gut microbiota plays an important role in parasite-host interactions and the induction of immune defense responses. Trichinella spiralis is an important zoonotic parasite that can directly or indirectly interact with the host in the gut. Changes in the gut microbiota following infection with T. ...
2023-08-07 | MTBLS7603 | MetaboLights
MetabolomicsSystem-wide analysis of short-term response to high temperature in Pinus radiata

Pinus radiata seedlings, the most widely planted pine species in the world, were exposed to temperatures within a range mimicking future scenarios based on current models of heat increase. The short-term heat response in P. radiata was studied in detail by exploring the metabolo...

2023-08-14 | MTBLS4567 | MetaboLights
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
MetabolomicsChlorogenic acid alters ileal microbiota and metabolites in broilers under immune stress

Immune stress in broilers can cause severe economic losses, chlorogenic acid is an effective plant extract for alleviating immune stress. This study investigates the effect of chlorogenic acid on the intestinal microbiota and metabolites of broilers under immune stress. 312 broilers were randomly...

2025-06-09 | MTBLS11790 | MetaboLights
Sort   by:  
 Page size