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ProteomicsT-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles
The present dataset contains proteomics data from extracellular vesicles steadily released by donor matched, cultured human CD4+ and CD8+ T cells and from extracellular vesicles released within the immunological synapse.
ORGANISM(S): Homo sapiens (Human) 
2022-05-31 | PXD033917 | Pride
T-cells Immunological synapse Extracellular vesicles 
ProteomicsAn integrated workflow for phosphopeptide identification in natural killer cells (NK) and their targets during immunological synapse formation
This protocol describes the identification and quantification of phosphopeptides during the dynamic formation of an immunological synapse. Isotope-labeled immune and target cells are mixed, cell-to-cell conjugates are stabilized by cross-linking, and isolated by fluorescence-activated cell sorting (...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-04 | MSV000090645 | MassIVE
GenomicsTumor cells impair immunological synapse formation via central nervous system-enriched metabolite
Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
PRJNA976338 | ENA
GenomicsSupplementing CD2 expression enhances CAR-T Cell Efficacy through Optimizing CAR-immunological Synapse formation
Supplementing CD2 expression enhances CAR-T Cell Efficacy through Optimizing CAR-immunological Synapse formation
PRJNA1233798 | ENA
GenomicsPhase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicity
PRJNA1167671 | ENA
UnknownTAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse.
Not available
S-EPMC4395477 | biostudies-literature
TranscriptomicsMicroarray dataset of gene transcription in mouse microglia and peripheral monocytes in contextual fear conditioning
Using Illumina MouseWG-6v2 microarrays, we investigated the gene transcription changes in microglia and peripheral monocytes after contextual fear conditioning of C57BL/6J mice. Mice were trained with or without a single minimized footshock stimulation (0-s or 2-s, 0.4 mA) and re-exposed to the trai...
ORGANISM(S): Mus musculus 
2022-10-28 | E-MTAB-12361 | biostudies-arrayexpress
UnknownRecruitment of dynein to the Jurkat immunological synapse.
Not available
S-EPMC1595445 | biostudies-literature
ProteomicsCD99-mediated immunological synapse formation potentiates CAR-T cell function
Cross-talks between actin and microtubules underly various cellular processes. Using immune synapse model and via cytoskeleton dynamics analyses, here, we demonstrate that CD99 is critical for the actin and microtubule cross-talks and the coordinated reorganization, mediating their physical linkage ...
ORGANISM(S): Mus musculus (Mouse) 
2025-07-18 | PXD039955 | Pride
Immunology Cd99 
UnknownActin polymerization-dependent activation of Cas-L promotes immunological synapse stability.
Not available
S-EPMC5121033 | biostudies-literature
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