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ProteomicsAntioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
The present study was carried out to determine the bioactivity of polysaccharides extracted from Euglena gracilis (EgPs). These were characterized by FT-IR and GC-MS. Cytotoxicity analyses (MTT) were performed on healthy human gingival fibroblast cell lines (HGF-1), obtaining an IC50 of 228.66 µg mL...
ORGANISM(S): Homo sapiens (Human) 
2022-12-21 | PXD029076 | Pride
Tmt-2plex. Sulfated polysaccharides Anticancer capacity Nutraceuticals Euglena gracilis Immunomodulatory capacity Antioxidant activity 
ProteomicsEngineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity.
Extracellular vesicles (EVs) are generated by all cells and systemic injection of allogenic EVs derived from epithelial or mesenchymal cells into humans and immunocompetent mice do not elicit any immune response despite the presence of ~1,200 proteins. Nevertheless, EVs from immune cells are purport...
ORGANISM(S): Homo sapiens (Human) 
2025-05-08 | PXD044115 | Pride
T cell function Cancer Extracellular vesicles Immune regulation 
ProteomicsEffect of menstrual blood-derived mesenchymal stromal cell secretomes on macrophage polarization: therapeutic insights
Menstrual blood-derived mesenchymal stromal cells (MenSCs) are a promising alternative source of MSCs for clinical applications due to their unique advantages, including easy isolation and high proliferative capacity. They possess immunomodulatory and regenerative capabilities, interacting with immu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-01-22 | MSV000096909 | MassIVE
UnknownImmortalized Canine Adipose-Derived Mesenchymal Stem Cells Maintain the Immunomodulatory Capacity of the Original Primary Cells.
Not available
S-EPMC10743981 | biostudies-literature
UnknownImproving the therapeutic profile of MSCs: Cytokine priming reduces donor-dependent heterogeneity and enhances their immunomodulatory capacity.
Not available
S-EPMC11872697 | biostudies-literature
ProteomicsImmunomodulatory, antioxidant, and potential anticancer activity of the polysaccharides of the fungus Fomitiporia chilensis
Fomitiporia species have aroused the interest of numerous investigations that reveal their biological activity and medicinal potential. The present investigation shows the antioxi-dant, anticancer, and immunomodulatory activity of acidic polysaccharides obtained from the fungus Fomitiporia chilensis...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD048361 | Pride
Fomitiporia chilensis Hgf-1 cells Uhplc-hrms Polysaccharides 
UnknownInflammatory Licensed hMSCs Exhibit Enhanced Immunomodulatory Capacity in a Biomaterial Mediated Manner.
Not available
S-EPMC10600978 | biostudies-literature
GenomicsInflammatory cytokines pre-treatment enhances the immunomodulatory property of hUC-MSCs
Inflammatory cytokines pre-treatment enhances the immunomodulatory property of hUC-MSCs
PRJNA930032 | ENA
UnknownAntioxidant, Immunomodulatory and Potential Anticancer Capacity of Polysaccharides (Glucans) from Euglena gracilis G.A. Klebs
Not available
S-EPMC9693019 | biostudies-literature
UnknownMesenchymal stromal cells express GARP/LRRC32 on their surface: effects on their biology and immunomodulatory capacity.
Not available
S-EPMC4309416 | biostudies-literature
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