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Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood; however, little is known about repertoire aging in other immune compa...
ORGANISM(S): Nothobranchius furzeri 
2026-03-30 | PXD029992 | Pride
Improving immune function during aging contributes to the extension of healthspan. However, little is known about interventions for overcoming immunosenescence. Here, we investigated whether syringaresinol (SYR), an activator of FOXO3, overcomes immunosenescence and the factors associated with this ...
ORGANISM(S): Mus musculus 
2017-02-08 | GSE75825 | GEO
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