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We report genomic imprinting effects in the arcuate nucleus, dorsal raphe nucleus, liver and muscle of adult female mice Examination of allele-specific gene expression hybrid mice generated from reciprocal crosses of CastEiJ x C57BL/6J mice
ORGANISM(S): Mus musculus 
Genomic imprinting results in the preferential expression of the paternal, or maternal allele of certain genes. We have performed a genome-wide characterization of imprinting in the mouse embryonic and adult brain using F1 hybrid mice generated from reciprocal crosses of CASTEiJ and C57BL/6J mice. ...
ORGANISM(S): Mus musculus 
Mouse embryo fibroblasts (MEFs) closely resemble mouse embryos and are convenient sources for biochemical studies when cell number may be limiting from mouse embryos. To derive the imprinting signature of MEFs and potentially detect novel imprinted genes we characterized them using strand- and allel...
ORGANISM(S): Mus musculus 
A method (termed Cellular Imprinting Proteomics, CImP) for the identification and quantification of the ocular surface proteome using a minimally invasive membrane filter device is described. Moreover, The CImP method was applied to profile the molecular alterations in the eyes of infants exposed to...
ORGANISM(S): Homo sapiens (Human) 
2020-07-23 | PXD014038 | Pride
DNA methylation is essential for embryonic development and implicated in the regulation of genomic imprinting. Genomic imprinting is established in the germline through parent-specific methylation of distinct cis-regulatory DNA sequences, called imprinting control regions (ICRs). Which factors bind ...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD034918 | Pride
Imprinting RNAseq
Genomic imprinting secures parent-specific gene expression through differential DNA methylation at imprinted control regions (ICRs). However, how unmethylated alleles resist de novo methylation remains unclear. Using an allelic Dlk1-Dio3 ICR methylation reporter and genome-wide loss-of-function scre...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-04 | PXD080456 | Pride
DNA methylation is an epigenetic mark associated with transposable element silencing and gene imprinting in flowering plants and mammals. In plants, imprinting occurs in the endosperm, which nourishes the embryo during seed development. We have profiled Arabidopsis DNA methylation genome-wide in the...
ORGANISM(S): Arabidopsis thaliana 
Murine long-term hematopoietic stem cells (HSCs), short-term HSCs and multipotent progenitor cells (MPPs) were isolated from bone marrow and expression profiled on Affy chips. The behavior of maternal-specific imprinting genes, particularly in the H19-Igf2 locus, was focused on, to see if any might...
ORGANISM(S): Mus musculus 
MLID imprinting disorders
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