Sort   by:  
 Page size 
TranscriptomicsEffects of in vitro maturation on oocyte gene expression
In vitro oocyte maturation (IVM) holds great promise as a tool for enhancing clinical treatment of infertility, enhancing availability of non human primates for development of disease models, and facilitating endangered species preservation. However, IVM outcomes have remained significantly below s...
ORGANISM(S): Macaca mulatta 
2009-05-20 | E-GEOD-11895 | biostudies-arrayexpress
MetabolomicsComprehensive multi-omics analysis reveals the influence of epigenetic mechanisms on porcine oocyte maturation
In vitro maturation (IVM) oocyte is a key component of assisted reproduction in pigs. Asynchronous nucleoplasmic maturation and incomplete cytoplasmic maturation is one of the key factors for impaired maturation and quality of oocytes matured in vitro. Although Single-omics techniques have been appl...
2025-08-27 | MTBLS12325 | MetaboLights
TranscriptomicsExtensive effects of in vitro oocyte maturation on rhesus monkey cumulus cell transcriptome
The elaboration of a quality oocyte is integrally linked to the correct developmental progression of cumulus cell phenotype. In humans and non-human primates, oocyte quality is diminished with in vitro maturation. To determine the changes in gene expression in rhesus monkey cumulus cells (CC) that o...
ORGANISM(S): Macaca mulatta 
2011-05-22 | E-GEOD-25288 | biostudies-arrayexpress
TranscriptomicsGene Expression Profiles in Immature and In vitro matured bovine Oocytes
In cattle, almost all fully grown vesicle stage oocytes (GV) have the ability to resume meisos, develop to Metaphase II stage (MII), support fertilization and progress through the early embryonic cycles in vitro. Yet without intensive selection, the majority fail to develop to the blastocyst stage. ...
ORGANISM(S): Bos taurus 
2011-04-25 | E-GEOD-23449 | biostudies-arrayexpress
TranscriptomicsTranscriptome profile of in vitro produced blastocysts derived from in vitro matured oocytes exposed to exogenous interleukin-6
This study explores the biological role of interleukin-6 (IL-6) as a supplement during in vitro maturation (IVM) of porcine oocytes, aiming to enhance embryonic development and reduce apoptosis following in vitro fertilization (IVF). The objective was to determine whether IL-6 supplementation alters...
ORGANISM(S): Sus scrofa 
2025-06-30 | E-MTAB-15241 | biostudies-arrayexpress
ProteomicsAnalysis of the proteome of individual equine cumulus complexes after maturation in-vitro and in-vivo
Maturation of oocytes under in-vitro conditions (IVM) results in impaired developmental competence compared to oocytes matured in-vivo. Oocytes are closely coupled to their cumulus complex (COC) with a bidirectional exchange of metabolites. Therefore, elucidation of aberrations in cumulus metabolism...
ORGANISM(S): Equus caballus (Horse) 
2019-11-12 | PXD011086 | Pride
In-vitro Cumulus cells In-vivo Lc-ms/ms Ivm 
ProteomicsBiphasic in vitro maturation (CAPA-IVM) on equine oocytes
In vitro maturation (IVM) of oocytes retrieved from ovum pick-up (OPU) or ovarian tissue (OT) is a standard approach for patients with specific conditions where prior hormonal stimulation is contraindicated. However, the developmental competence of oocytes matured in vitro is still inferior to that ...
ORGANISM(S): Equus caballus (Horse) 
2025-06-07 | PXD060584 | Pride
Timstof scp Oocyte Equine 
TranscriptomicsTranscriptional profiling of cumulus cells entoured the oocyte after in vitro or in vivo maturation in bovine (Bos taurus)
In vitro maturation (IVM) of the oocytes is a routine method in bovine embryo production. The competence of bovine oocytes to develop into embryo after IVM and in vitro fertilization (IVF) is lower as compared to in vivo preovulatory oocytes. Cumulus cells (CC) that enclose an oocyte are involved in...
ORGANISM(S): Bos taurus 
2011-08-08 | E-GEOD-31261 | biostudies-arrayexpress
ProteomicsTreatment of human oocytes with extracellular vesicles from follicular fluid during rescue in vitro maturation enhances maturation rates and modulates oocyte proteome and ultrastructure
This project aimed to elucidate whether human follicular fluid–derived extracellular vesicles (ffEVs) enhance oocyte maturation during rescue in vitro maturation (rIVM). We characterised the protein cargo of ffEVs isolated from follicles containing oocytes at different maturation stages (GV, GVBD, a...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD073018 | Pride
Follicular fluid Extracellular vesicles Human oocyte In vitro maturation Single-cell proteomic analysis 
ProteomicsSingle-cell quantitative proteomic analysis of oocyte maturation revealed high heterogeneities in human in vitro matured oocytes
In this study we investigated the protein expression patterns during human oocyte in vitro and in vivo maturation (IVO) by single-cell quantitative proteomic analysis of 36 human oocytes. Among 2,094 proteins quantified in 34 oocytes (GV: 11 oocytes, IVM: 12 oocytes, IVO: 11 oocytes), 224 were diffe...
ORGANISM(S): Homo sapiens (Human) 
2022-08-02 | PXD023366 | Pride
Human oocyte maturation Single cell proteomics 
Sort   by:  
 Page size