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ProteomicsThe preclinical evaluation of a second-generation antivenom for treating snake envenoming in India
In this study, by employing chromatographic purification of the bulk, we have significantly enhanced the preclinical performance of the conventional Indian antivenom product. The effectiveness of the test batches of this ‘second-generation’ antivenom was evaluated using a variety of in vitro and in ...
ORGANISM(S): Equus caballus (Horse) 
2022-04-04 | PXD029436 | Pride
Snakebite Antivenoms Second-generation antivenoms 
ProteomicsTo the islands their own: Venomics of the enigmatic Andaman cobra (N. sagittifera) and the preclinical failure of Indian antivenoms in Andaman and Nicobar Islands
In this study, we unveil the venom composition, biochemistry, pharmacological activity, and potency of the Andaman cobra (N. sagittifera).
ORGANISM(S): Naja naja Naja sagittifera 
2022-02-17 | PXD025362 | Pride
Naja sagittifera Proteomics Indian antivenoms Naja naja 
UnknownMultilevel Comparison of Indian Naja Venoms and Their Cross-Reactivity with Indian Polyvalent Antivenoms.
Not available
S-EPMC10142961 | biostudies-literature
UnknownVenomics of the Enigmatic Andaman Cobra (Naja sagittifera) and the Preclinical Failure of Indian Antivenoms in Andaman and Nicobar Islands.
Not available
S-EPMC8573199 | biostudies-literature
UnknownEfficacy of Indian polyvalent snake antivenoms against Sri Lankan snake venoms: lethality studies or clinically focussed in vitro studies.
Not available
S-EPMC4882578 | biostudies-literature
ProteomicsCompositional analysis of venom in three species of Indian cobra (Naja) and their cross-reactivity with Indian polyvalent Antivenom
The study represents genus-wide proteomics analysis of venom composition across Naja (N. naja, N. oxiana and N. kaouthia) found in mainland India. Venoms from Naja species were fractionated using RP-HPLC and subjected to MS/MS analysis. Indian polyvalent antivenom immunoprofiling was performed again...
ORGANISM(S): Naja naja Naja oxiana Naja kaouthia 
2023-05-10 | PXD027361 | Pride
Naja oxiana Naja naja Polyvalent antivenom Thermofisher qexactive hf Antivenomics Naja kaouthia Venomics Venom variation Snakebites 
UnknownCross-Neutralisation of In Vitro Neurotoxicity of Asian and Australian Snake Neurotoxins and Venoms by Different Antivenoms.
Not available
S-EPMC5086662 | biostudies-literature
ProteomicsExplaining Echis envenoming: Transcriptomic and proteomic profiling of Echis carinatus venom
In India, venom research has largely focussed on the ‘big four’ snakes that are greatly responsible for the burden of snakebite in the Indian subcontinent. This study aims to advance understanding of saw-scaled viper venoms from India, we implemented a multi-faceted approach. We sequenced the venom ...
ORGANISM(S): Echis carinatus 
2025-08-04 | PXD064002 | Pride
Antivenom In vivo Proteome Echis carinatus Transcriptome 
UnknownElusive elapids: biogeographic venom variation in Indian kraits and its repercussion on snakebite therapy.
Not available
S-EPMC11579489 | biostudies-literature
UnknownBiogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy.
Not available
S-EPMC7924803 | biostudies-literature
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