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In this project we have identifed and linear and spliced HLA-I bound peptides to LM-MEl-44, 53 and 33 cell lines in two different condition, treated and not treated with interferone gamma.
ORGANISM(S): Homo sapiens (Human) 
2020-09-25 | PXD014397 | Pride
2’3’-cyclic GMP-AMP (cGAMP) is a cyclic dinucleotide second messenger in which guanosine and adenosine are connected by one 3’-5’ and one 2’-5’ phosphodiester linkage. It is formed in the cytosol upon detection of pathogenic DNA by the enzyme guanosine-monophosphate-adenosine monophosphate synthase ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057395 | Pride
Necroptosis is a lytic and inflammatory form of cell death that is highly constrained to mitigate detrimental collateral tissue damage and impaired immunity. These constraints make it difficult to define the relevance of necroptosis in diseases such as chronic and persistent viral infections and wit...
ORGANISM(S): Mus musculus 
2023-03-12 | GSE224066 | GEO
Oncolytic virus therapy is a promising direction for cancer treatment. Numerous oncolytic virus strains are under development or examined in clinical trials, there are examples of FDA approved virus vaccines. Although evident progress exists, oncolytic viruses still suffer low efficiency and the mec...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD022836 | Pride
Oncolytic virus therapy is a promising direction for cancer treatment. Numerous oncolytic virus strains are under development or examined in clinical trials, there are examples of FDA approved virus vaccines. Although evident progress exists, oncolytic viruses still suffer low efficiency and the mec...
ORGANISM(S): Homo sapiens (Human) 
2022-02-03 | PXD022906 | Pride
A necroptosis-independent function of RIPK3 promotes immune dysfunction and prevents control of chronic LCMV infection
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