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MetabolomicsIntegrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non-functioning pituitary adenomas

Pituitary adenomas constitute 10 to 25% of intracranial tumors, rendering them one of the most prevalent types of brain tumors. While the majority of pituitary adenomas are benign, ~35% exhibit invasive behavior. Compared with their non-invasive counterparts, invasive pituitary adenomas are more ...

2025-12-09 | MTBLS13478 | MetaboLights
ProteomicsLong-Chain Acyl Coenzyme A Dehydrogenase, a Key Player in Metabolic Rewiring/Invasiveness in Experimental Tumors and Human Mesothelioma Cell Lines
Cross-species investigations of cancer invasiveness are a new approach that has already identified new biomarkers which are potentially useful for improving tumor diagnosis and prognosis in clinical medicine and veterinary science. In this study, we combined proteomic analysis of four experimental r...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-06-20 | PXD042942 | Pride
Malignant mesothelioma  metabolism  mitochondria  long-chain specific acyl-coa dehydrogenase  fatty acid β-oxidation  biomarker 
ProteomicsProteomic analysis of the invasiveness of human bladder cancer cells
To identification of key drivers involved in the development of muscle invasive bladder cancer, which displays poor prognosis, we isolated one subpopulation of human 5637 bladder cancer cells with highly invasiveness and the other subpopulation of 5637 cells with low invasiveness by Transwell method...
ORGANISM(S): Homo sapiens (Human) 
2018-03-15 | PXD007709 | Pride
Tmt6 Invasiveness Human Bladder cancer cells 
ProteomicsMuscular invasiveness in bladder cancer
Patients with bladder cancer need frequent controls over long follow-up time due to high recurrence rate and risk of conversion to muscle invasive cancer with poor prognosis. We identified cancer-related molecular signatures in apparently healthy bladder in patients with subsequent muscular invasive...
ORGANISM(S): Homo sapiens (Human) 
2018-10-26 | PXD010260 | Pride
Human Bladder cancer Label-free proteomics Q-exactive-hf 
ProteomicsA proteomic approach to identify endosomal cargoes controlling cancer invasiveness
We have developed a proteomic approach to identify endosomal cargoes that contribute to cancer invasiveness.
ORGANISM(S): Homo sapiens (Human) 
2017-01-18 | PXD003745 | Pride
Silac  label-free  cancer  recyclome  orbitrap 
ProteomicsIntegrated proteomic and metabolomic profiling reveals molecular signatures underlying invasiveness in non-functioning pituitary adenoma
Pituitary adenomas constitute 10 to 25% of intracranial tumors, rendering them one of the most prevalent types of brain tumors. While the majority of pituitary adenomas are benign, ~35% exhibit invasive behavior. Compared with their non-invasive counterparts, invasive pituitary adenomas are more cha...
ORGANISM(S): Homo Sapiens 
2025-12-09 | PXD071754 |
TranscriptomicsGene differential expressions between cell subpopulations with high invasiveness (invaded) and low invasiveness (non-invaded) in human lung cancer H460 cell line
Cell populations with different invasiveness were isolated and collected with cell culture inserts of Boyden-type cell invasion chambers coated with 1xBME (base membrane extract). Cells that invaded to bottom chamber were collected as cell population with high-invasiveness , and cells that remained ...
ORGANISM(S): Homo sapiens 
2015-07-15 | GSE68916 | GEO
GenomicsSAGA Complex Subunits in Candida albicans Differentially Regulate Filamentation, Invasiveness and Biofilm Formation
SAGA Complex Subunits in Candida albicans Differentially Regulate Filamentation, Invasiveness and Biofilm Formation
PRJNA798386 | ENA
GenomicsDNA Methylation-based Stratification of Pediatric Thyroid Carcinoma Invasiveness [1st batch]
DNA Methylation-based Stratification of Pediatric Thyroid Carcinoma Invasiveness [1st batch]
PRJNA1259388 | ENA
GenomicsDNA Methylation-based Stratification of Pediatric Thyroid Carcinoma Invasiveness [2nd batch]
DNA Methylation-based Stratification of Pediatric Thyroid Carcinoma Invasiveness [2nd batch]
PRJNA1374272 | ENA
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