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UnknownA PI3K/AKT Scaffolding Protein, IQ Motif-Containing GTPase Associating Protein 1 (IQGAP1), Promotes Head and Neck Carcinogenesis.
Not available
S-EPMC6942630 | biostudies-literature
GenomicsDNase I hypersensitivity and algorithmic prediction of TF binding in early pancreatic mES directed differentiation
This dataset uses DNase-seq to profile the genome-wide DNase I hypersensitivity of mES and mES-derived cells along an early pancreatic lineage and provides the locations of putative Transcription Factor (TF) binding sites using the PIQ algorithm. DNase-seq takes advantage of the preferential cutting...
ORGANISM(S): Mus musculus 
2014-01-19 | E-GEOD-53776 | biostudies-arrayexpress
UnknownNovel Alzheimer risk factor IQ motif containing protein K is abundantly expressed in the brain and is markedly increased in patients with Alzheimer's disease.
Not available
S-EPMC9344928 | biostudies-literature
UnknownSertoli cell survival and barrier function are regulated by miR-181c/d-Pafah1b1 axis during mammalian spermatogenesis.
Not available
S-EPMC9411099 | biostudies-literature
UnknownIQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation.
Not available
S-EPMC4858964 | biostudies-literature
TranscriptomicsIQGAP2 knockout model of hepatocellular carcinoma
Whole body knockout mice lacking IQ-motif containing GTPase-activating protein 2 (IQGAP2) develop spontaneous hepatocellular carcinoma (HCC) at the age of 12 months and older (Schmidt et al., 2008). Hepatic transcript expression profiles were obtained for IQGAP2 knockout and wild-type control mice o...
ORGANISM(S): Mus musculus 
2013-12-13 | E-GEOD-46646 | biostudies-arrayexpress
UnknownThe tree of life of copper-containing amine oxidases.
Not available
S-EPMC12058724 | biostudies-literature
TranscriptomicsHuman nasopharyngeal carcinoma
To uncover the oncogenic pathways of nasopharyngeal carcinoma, gene expression profiles of primary NPC cell strains and NPC-derived cell lines were conducted and analyzed in depth. Keywords: Oncogenesis Gene expression profiles of 9 primary NPC cell strains and 5 NPC-derived cell lines were analyz...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-14262 | biostudies-arrayexpress
ProteomicsIQGAP3 bridges matrix stiffness with glioma stem cell maintenance and radioresistance by stabilizing SOX2
Drivers of therapeutic resistance in cancer include evolution of tumor cell heterogeneity and the tumor microenvironment (TME). Here, we found that increased matrix stiffness promotes radioresistance in glioblastoma (GBM) and maintains the tumor cell hierarchy. Differential gene expression revealed ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD072748 | Pride
Cancer stem cell Glioma stem cell Glioblastoma Radiation Matrix stiffness Iqgap3 Sox2 
ProteomicsIQGAP3 bridges matrix stiffness with glioma stem cell maintenance and radioresistance by stabilizing SOX2
Drivers of therapeutic resistance in cancer include evolution of tumor cell heterogeneity and the tumor microenvironment (TME). Here, we found that increased matrix stiffness promotes radioresistance in glioblastoma (GBM) and maintains the tumor cell hierarchy. Differential gene expression revealed ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-11 | PXD072725 | Pride
Cancer stem cell Glioma stem cell Glioblastoma Radiation Matrix stiffness Iqgap3 Sox2 
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